TNF
tumor necrosis factor
Synonyms:
DIF, TNF-alpha, TNFA, TNFSF2
Species:
Human TNF (7124), Mouse Tnf (21926), Rat Tnf (24835), dog TNF (403922), domestic cat TNF (493755), Horse TNF (100033834), Goat TNF (100861232), cow TNF (280943), sheep TNF (443540), Domestic Rabbit TNF (100009088) ...More
UniProtKB ID:
Gene ID:
- Human(7124) Summary: This gene encodes a multifunctional proinflammatory cytokine that belongs to the tumor necrosis factor (TNF) superfamily. This cytokine is mainly secreted by macrophages. It can bind to, and thus functions through its receptors TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. This cytokine is involved in the regulation of a wide spectrum of biological processes including cell proliferation, differentiation, apoptosis, lipid metabolism, and coagulation. This cytokine has been implicated in a variety of diseases, including autoimmune diseases, insulin resistance, and cancer. Knockout studies in mice also suggested the neuroprotective function of this cytokine. [provided by RefSeq, Jul 2008]
- Mouse(21926) tumor necrosis factor
- Rat(24835) tumor necrosis factor
- dog(403922) tumor necrosis factor
- domestic cat(493755) tumor necrosis factor
- Horse(100033834) tumor necrosis factor
- Goat(100861232) tumor necrosis factor alpha
- cow(280943) tumor necrosis factor
- sheep(443540) tumor necrosis factor
- Domestic Rabbit(100009088) tumor necrosis factor
- domestic guinea pig(100135630) tumor necrosis factor
- naked mole-rat(101718432) tumor necrosis factor
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ELISA
Product Number
Description
Species
Porcine Tumor Necrosis Factor α ELISA Kit, for serum, plasma and cell culture supernatant,
Species
Bovine TNFα / Tumor Necrosis Factor alpha ELISA Kit, for serum, plasma and cell culture supernatants,
Species
cow
Canine TNF / Tumor Necrosis Factor ELISA Kit, for serum, plasma and cell culture supernatants,
Species
dog
Mouse Tumor Necrosis Factor α ELISA Kit, for serum, plasma and cell culture supernatant,
Species
mouse
Small Molecule - Antagonist
Product Number
Description
Species
Antibodies
Product Number
Description
Species Reactivity
Application
Monoclonal Anti-TNF antibody produced in mouse, clone 1C3-A1-F4, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
western blot
western blot
Monoclonal Anti-TNF antibody produced in mouse, clone M1-C4, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-Tumor Necrosis Factor-α antibody produced in goat, affinity isolated antibody, lyophilized powder,
Species Reactivity
mouse
Application
ELISA
flow cytometry
immunofluorescence
neutralization
western blot
flow cytometry
immunofluorescence
neutralization
western blot
Anti-Tumor Necrosis Factor-α antibody produced in goat, affinity isolated antibody, lyophilized powder,
Species Reactivity
pig
Application
ELISA
immunohistochemistry
neutralization
western blot
immunohistochemistry
neutralization
western blot
Monoclonal Anti-Tumor Necrosis Factor-α–Fluorescein antibody produced in mouse, clone 6402.31, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
flow cytometry
Small Molecule - Inhibitor
Product Number
Description
Species
Proteins
Product Number
Description
Species
TNF-α human, Animal-component free, recombinant, expressed in E. coli, suitable for cell culture,
Species
human
TNFα, low endotoxin, His tagged human, recombinant, expressed in E. coli, ≥80% (SDS-PAGE),
Species
human
Tumor Necrosis Factor-α from mouse, TNF-α, recombinant, expressed in E. coli, powder, suitable for cell culture,
Species
mouse
Tumor Necrosis Factor-α human, Xeno-free, recombinant, expressed in HEK 293 cells, suitable for cell culture,
Species
human