TAB2
TGF-beta activated kinase 1/MAP3K7 binding protein 2
Synonyms:
CHTD2, MAP3K7IP2
Species:
Human TAB2 (23118), Mouse Tab2 (68652), Rat Tab2 (308267), dog TAB2 (484028), chicken TAB2 (421622), Zebrafish tab2 (494163), fruit fly Tab2 (37216), naked mole-rat Tab2 (101698406), domestic guinea pig Tab2 (100717911), sheep TAB2 (101122114) ...More
UniProtKB ID:
Gene ID:
- Human(23118) Summary: The protein encoded by this gene is an activator of MAP3K7/TAK1, which is required for for the IL-1 induced activation of nuclear factor kappaB and MAPK8/JNK. This protein forms a kinase complex with TRAF6, MAP3K7 and TAB1, thus serves as an adaptor linking MAP3K7 and TRAF6. This protein, TAB1, and MAP3K7 also participate in the signal transduction induced by TNFSF11/RANKl through the activation of the receptor activator of NF-kappB (TNFRSF11A/RANK), which may regulate the development and function of osteoclasts. [provided by RefSeq, Jul 2008]
- Mouse(68652) TGF-beta activated kinase 1/MAP3K7 binding protein 2
- Rat(308267) TGF-beta activated kinase 1/MAP3K7 binding protein 2
- dog(484028) TGF-beta activated kinase 1/MAP3K7 binding protein 2
- chicken(421622) TGF-beta activated kinase 1/MAP3K7 binding protein 2
- Zebrafish(494163) TGF-beta activated kinase 1/MAP3K7 binding protein 2
- fruit fly(37216) TAK1-associated binding protein 2
- naked mole-rat(101698406) TGF-beta activated kinase 1/MAP3K7 binding protein 2
- domestic guinea pig(100717911) TGF-beta activated kinase 1/MAP3K7 binding protein 2
- sheep(101122114) TGF-beta activated kinase 1/MAP3K7 binding protein 2
- cow(540203) TGF-beta activated kinase 1/MAP3K7 binding protein 2
- Horse(100060433) TGF-beta activated kinase 1/MAP3K7 binding protein 2
- domestic cat(101098714) TGF-beta activated kinase 1/MAP3K7 binding protein 2
Custom & Knockdown Gene Products
siRNA
Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.
shRNA
Shop the largest, most validated shRNA collection and build your own clone sets.
Custom Gene Products
We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.
Antibodies
Product Number
Description
Species Reactivity
Application
Anti-TAB-2 Antibody, clone 1D5.2, clone 1D5.2, from mouse,
Species Reactivity
human
Application
western blot
Anti-TAB2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Species Reactivity
human
Application
immunofluorescence
Anti-TAB2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Species Reactivity
human
Application
immunohistochemistry
Anti-TAB2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Species Reactivity
human
Application
immunohistochemistry