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PGGT1B

protein geranylgeranyltransferase type I, beta subunit

Synonyms:
BGGI, GGTI
Species:
Human PGGT1B (5229), Mouse Pggt1b (225467), Rat Pggt1b (81746), Zebrafish pggt1b (570808), chicken PGGT1B (770633), domestic cat PGGT1B (101089829), naked mole-rat Pggt1b (101723510), domestic guinea pig Pggt1b (100735292), dog PGGT1B (481440), sheep PGGT1B (101123045)
UniProtKB ID:
P53609, Q5MJP9
Gene ID:
  • Human(5229) Summary: Protein geranylgeranyltransferase type I (GGTase-I) transfers a geranylgeranyl group to the cysteine residue of candidate proteins containing a C-terminal CAAX motif in which 'A' is an aliphatic amino acid and 'X' is leucine (summarized by Zhang et al., 1994 [PubMed 8106351]
  • Mouse(225467) protein geranylgeranyltransferase type I, beta subunit
  • Rat(81746) protein geranylgeranyltransferase type I, beta subunit
  • Zebrafish(570808) protein geranylgeranyltransferase type I, beta subunit
  • chicken(770633) protein geranylgeranyltransferase type I, beta subunit
  • domestic cat(101089829) protein geranylgeranyltransferase type I, beta subunit
  • naked mole-rat(101723510) protein geranylgeranyltransferase type I, beta subunit
  • domestic guinea pig(100735292) protein geranylgeranyltransferase type I, beta subunit
  • dog(481440) protein geranylgeranyltransferase type I, beta subunit
  • sheep(101123045) protein geranylgeranyltransferase type I, beta subunit
  • cow(509322) protein geranylgeranyltransferase type I, beta subunit

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Antibodies

Product Number
Description
Species Reactivity
Application
WH0005229M2
Monoclonal Anti-PGGT1B antibody produced in mouse, clone 5E4, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human, mouse, rat
Application
ELISA
immunofluorescence
western blot

Small Molecule - Inhibitor

Product Number
Description
Species
G5169
GGTI 298 trifluoroacetate salt hydrate, ≥90% (HPLC), film,
Species
human
G5294
GGTI-2133, ≥98% (HPLC), solid,
Species
human
259926
Itaconic anhydride, 95%,
Species
human

esiRNA

Product Number
Description
Species
EHU112171
MISSION® esiRNA, targeting human PGGT1B (2),
Species
human
EMU041131
MISSION® esiRNA, targeting mouse Pggt1b,
Species
mouse