Skip to Content
MilliporeSigma

NDUFA1

NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 1, 7.5kDa

Synonyms:
CI-MWFE, MWFE, ZNF183
Species:
UniProtKB ID:
Gene ID:
  • Human(4694) Summary: The human NDUFA1 gene codes for an essential component of complex I of the respiratory chain, which transfers electrons from NADH to ubiquinone. It has been noted that the N-terminal hydrophobic domain has the potential to be folded into an alpha-helix spanning the inner mitochondrial membrane with a C-terminal hydrophilic domain interacting with globular subunits of complex I. The highly conserved two-domain structure suggests that this feature is critical for the protein function and might act as an anchor for the NADH:ubiquinone oxidoreductase complex at the inner mitochondrial membrane. However, the NDUFA1 peptide is one of about 31 components of the 'hydrophobic protein' (HP) fraction of complex I which is involved in proton translocation. Thus the NDUFA1 peptide may also participate in that function. [provided by RefSeq, Jul 2008]
  • Mouse(54405) NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 1
  • Rat(363441) NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 1
  • dog(481033) NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 1, 7.5kDa
  • domestic cat(101085609) NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 1, 7.5kDa
  • chicken(772150) NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 1, 7.5kDa
  • naked mole-rat(101713738) NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 1, 7.5kDa
  • Zebrafish(415243) NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 1
  • cow(327673) NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 1, 7.5kDa
  • sheep(100216464) NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 1, 7.5kDa

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

    Shop the largest, most validated shRNA collection and build your own clone sets.

  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

Antibodies

Product Number
Description
Species Reactivity
Application
Monoclonal Anti-NDUFA1 antibody produced in mouse, clone 3B9-1A1, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
western blot
Monoclonal Anti-NDUFA1 antibody produced in mouse, clone 2A4, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
Anti-NDUFA1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
Anti-NDUFA1 antibody produced in rabbit, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
western blot
Anti-NDUFA1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Species Reactivity
human
Application
immunofluorescence

Small Molecule - Inhibitor

Product Number
Description
Species
Metformin hydrochloride, Pharmaceutical Secondary Standard; Certified Reference Material,
Species
human
Metformin hydrochloride solution, 1.0 mg/mL in methanol (as free base), ampule of 1 mL, certified reference material, Cerilliant®,
Species
human
1,1-Dimethylbiguanide hydrochloride, 97%,
Species
human
Metformin hydrochloride, European Pharmacopoeia (EP) Reference Standard,
Species
human
Metformin hydrochloride, United States Pharmacopeia (USP) Reference Standard,
Species
human