Skip to Content
MilliporeSigma

MRPL22

mitochondrial ribosomal protein L22

Synonyms:
L22mt, MRP-L22, MRP-L25, RPML25
Species:
UniProtKB ID:
Gene ID:
  • Human(29093) Summary: Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein that belongs to the L22 ribosomal protein family. A pseudogene corresponding to this gene is found on chromosome 4q. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
  • Mouse(216767) mitochondrial ribosomal protein L22
  • Rat(287302) mitochondrial ribosomal protein L22
  • naked mole-rat(101714422) mitochondrial ribosomal protein L22
  • domestic guinea pig(100729278) mitochondrial ribosomal protein L22
  • Zebrafish(100142645) mitochondrial ribosomal protein L22
  • fruit fly(32662) mitochondrial ribosomal protein L22
  • chicken(416253) mitochondrial ribosomal protein L22
  • dog(479320) mitochondrial ribosomal protein L22
  • domestic cat(101095716) mitochondrial ribosomal protein L22
  • sheep(101110505) mitochondrial ribosomal protein L22
  • cow(614639) mitochondrial ribosomal protein L22

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

    Shop the largest, most validated shRNA collection and build your own clone sets.

  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

Antibodies

Product Number
Description
Species Reactivity
Application
Anti-MRPL22 antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
ELISA
western blot
Anti-MRPL22 antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
western blot
Anti-MRPL22 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry

western blot

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting mouse Mrpl22,
Species
mouse