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ARHGEF12

Rho guanine nucleotide exchange factor (GEF) 12

Synonyms:
LARG, PRO2792
Species:
UniProtKB ID:
Gene ID:
  • Human(23365) Summary: Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli working through G protein-coupled receptors. The encoded protein may form a complex with G proteins and stimulate Rho-dependent signals. This protein has been observed to form a myeloid/lymphoid fusion partner in acute myeloid leukemia. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2010]
  • Mouse(69632) Rho guanine nucleotide exchange factor (GEF) 12
  • Rat(367072) Rho guanine nucleotide exchange factor (GEF) 12
  • domestic cat(101085657) Rho guanine nucleotide exchange factor (GEF) 12
  • dog(479409) Rho guanine nucleotide exchange factor (GEF) 12
  • Zebrafish(571031) Rho guanine nucleotide exchange factor (GEF) 12
  • chicken(419752) Rho guanine nucleotide exchange factor (GEF) 12
  • naked mole-rat(101716885) Rho guanine nucleotide exchange factor (GEF) 12
  • domestic guinea pig(100723937) Rho guanine nucleotide exchange factor (GEF) 12
  • sheep(101117190) Rho guanine nucleotide exchange factor (GEF) 12
  • Domestic Rabbit(100340118) Rho guanine nucleotide exchange factor (GEF) 12
  • cow(503575) Rho guanine nucleotide exchange factor (GEF) 12

Custom & Knockdown Gene Products

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti-ARHGEF12 antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
ELISA
western blot
Anti-ARHGEF12 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry
Anti-Leukemia-associated RhoGEF/LARG Antibody, clone 13D2.1, clone 13D2.1, from mouse,
Species Reactivity
human
Application
immunocytochemistry
western blot

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human ARHGEF12,
Species
human