ABCG2
ATP-binding cassette, sub-family G (WHITE), member 2
Synonyms:
ABC15, ABCP, BCRP, BCRP1, BMDP, CD338, CDw338, EST157481, GOUT1, MRX, MXR, MXR1, UAQTL1
Species:
Human ABCG2 (9429), Mouse Abcg2 (26357), Rat Abcg2 (312382), domestic guinea pig Abcg2 (100723442), domestic cat ABCG2 (101094017), chicken ABCG2 (423767), dog ABCG2 (478472), Horse ABCG2 (100034164), cow ABCG2 (536203), sheep ABCG2 (780508) ...More
UniProtKB ID:
Gene ID:
- Human(9429) Summary: The membrane-associated protein encoded by this gene is included in the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the White subfamily. Alternatively referred to as a breast cancer resistance protein, this protein functions as a xenobiotic transporter which may play a major role in multi-drug resistance. It likely serves as a cellular defense mechanism in response to mitoxantrone and anthracycline exposure. Significant expression of this protein has been observed in the placenta, which may suggest a potential role for this molecule in placenta tissue. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2012]
- Mouse(26357) ATP-binding cassette, sub-family G (WHITE), member 2
- Rat(312382) ATP-binding cassette, subfamily G (WHITE), member 2
- domestic guinea pig(100723442) ATP-binding cassette, sub-family G (WHITE), member 2
- domestic cat(101094017) ATP-binding cassette, sub-family G (WHITE), member 2
- chicken(423767) ATP-binding cassette, sub-family G (WHITE), member 2
- dog(478472) ATP-binding cassette, sub-family G (WHITE), member 2
- Horse(100034164) ATP-binding cassette, sub-family G (WHITE), member 2
- cow(536203) ATP-binding cassette, sub-family G (WHITE), member 2
- sheep(780508) ATP-binding cassette, sub-family G (WHITE), member 2
- Domestic Rabbit(100008640) ATP-binding cassette, sub-family G (WHITE), member 2
- Goat(100860857) ATP-binding cassette, sub-family G (WHITE), member 2
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Antibodies
Product Number
Description
Species Reactivity
Application
Monoclonal Anti-ABCG2 antibody produced in mouse, clone 1G1, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
western blot
western blot
Anti-ABCG2 antibody produced in rabbit, ,
Species Reactivity
human, mouse, rat
Application
western blot
Anti-BCRP Antibody, clone BXP-34, culture supernatant, clone BXP-34, Chemicon®,
Species Reactivity
human
Application
immunocytochemistry
immunohistochemistry
immunohistochemistry
Anti-ABCG2 antibody produced in rabbit, ,
Species Reactivity
human, mouse, rat
Application
western blot
Anti-BCRP (ABCG2) Antibody, clone 10K5 , ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Species Reactivity
human, mouse
Application
immunocytochemistry
immunohistochemistry
western blot
immunohistochemistry
western blot
Cell Lines
Product Number
Description
Species
Proteins
Product Number
Description
Species
SB-BCRP-M-PREDEASY-ATPase kit, membrane based kit for Human BCRP ATPase Transport Assays,
Species
human