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Alteration in Intracellular Zn

Frontiers in molecular neuroscience (2018-01-10)
Xin Li, Wei Yang, Lin-Hua Jiang
ABSTRACT

Transient receptor potential melastatin-related 2 (TRPM2) channel, a molecular sensor for reactive oxygen species (ROS), plays an important role in cognitive dysfunction associated with post-ischemia brain damage thought to result from ROS-induced TRPM2-dependent neuronal death during reperfusion. Emerging evidence further suggests that an alteration in the Zn

MATERIALS
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Sigma-Aldrich
N,N,N′,N′-Tetrakis(2-pyridylmethyl)ethylenediamine