8.02407

Quinoline

for synthesis

• Synonym(s): Quinoline, 1-Azanaphthalene
• Empirical Formula (Hill Notation): C₉H₇N
• CAS Number: 91-22-5
• Molecular Weight: 129.16
• UNSPSC Code: 12352005
• EC Index Number: 202-051-6
• NACRES: NA.22
• MDL number: MFCD00006736
• Assay: ≥97.0% (GC)
• Form: liquid

Properties

• vapor pressure: 11 Pa ( 25 °C)
• Quality Segment: 200
• assay: ≥97.0% (GC)
• form: liquid
• autoignition temp.: 480 °C
• potency: 270 mg/kg LD₅₀, oral (Rat), 590 mg/kg LD₅₀, skin (Rabbit)
• expl. lim.: 1.2-7 % (v/v)
• pH: 7.3 (20 °C, 5 g/L in H₂O)
• bp: 237-238 °C/1013 hPa
• mp: -15 °C
• transition temp: flash point 107 °C
• solubility: 6 g/L
• density: 1.09 g/cm³ at 25 °C
• storage temp.: 2-30°C
• SMILES string: n1c2c(ccc1)cccc2
• InChI: 1S/C9H7N/c1-2-6-9-8(4-1)5-3-7-10-9/h1-7H
• InChI key: SMWDFEZZVXVKRB-UHFFFAOYSA-N

Description

Application

• Application of quinoline derivatives in third-generation photovoltaics: This article reviews the latest developments in quinoline derivatives, highlighting their implementation in third-generation photovoltaics, showcasing advancements in the field (Lewinska et al., 2021).


• Recent advances in the synthesis of biologically and pharmaceutically active quinoline and its analogues: A comprehensive review on the synthesis methods of quinoline, discussing their biological and pharmaceutical applications, focusing on innovative synthetic routes (Weyesa et al., 2020).


• Recent advances in chemistry and therapeutic potential of functionalized quinoline motifs: This review explores the medicinal potential of quinoline and its functionalized derivatives, emphasizing their utility in drug development (Ajani et al., 2022).


• Comprehensive review on current developments of quinoline-based anticancer agents: This review article covers the role of quinoline compounds in anticancer drug development, highlighting recent progress and new drugs based on the quinoline scaffold (Jain et al., 2019).

Analysis Note

Assay (GC, area%): ≥ 97.0 % (a/a)
Density (d 20 °C/ 4 °C): 1.092 - 1.094
Identity (IR): passes test

Safety Information

• pictograms: GHS06,GHS08,GHS09
• signalword: Danger
• hcodes: H301 - H312 - H315 - H319 - H341 - H350 - H411
• pcodes: P202 - P273 - P280 - P301 + P310 - P302 + P352 + P312 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 3 Oral - Acute Tox. 4 Dermal - Aquatic Chronic 2 - Carc. 1B - Eye Irrit. 2 - Muta. 2 - Skin Irrit. 2
• Storage Class: 6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• wgk: WGK 2
• flash_point_f: 224.6 °F
• flash_point_c: 107 °C