45124
Elastase from porcine pancreas
powder, white, ≥10 U/mg
Synonym(s):
Elastase from hog pancreas, Pancreatopeptidase E
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About This Item
CAS Number:
EC Number:
MDL number:
UNSPSC Code:
12352204
NACRES:
NA.54
Recommended Products
biological source
Porcine pancreas
form
powder
specific activity
≥10 U/mg
mol wt
Mr ~25000
color
white
storage temp.
−20°C
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Biochem/physiol Actions
Elastase hydrolyses elastin, the specific protein of elastic fibers, and digests hemoglobin, casein and fibrin.
Unit Definition
1 U corresponds to the amount of enzyme which liberates 1 μmol 4-nitroaniline per minute at 25°C and pH 7.8 (succinyl-(L-Ala)3-4-nitroanilide as substrate)
One unit will hydrolyze 1.0 μmole of N-succinyl-L-Ala-Ala-Ala-p-nitroanilide per min, pH 8.0 at 25 °C.
Other Notes
Cleaves polyalanyl-lysine peptides at the alanyl-lysine bond, review; Review, elastase-type proteases
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Certificates of Analysis (COA)
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Huanlei Zhu et al.
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L Robert
Pathologie-biologie, 36(9), 1101-1107 (1988-11-01)
Elastin in the most resistant fibrous protein of the organisms. Its degradation is catalysed by proteases designated as elastases. Elastic fibers appeared during phylogenesis at the level of the first Vertebrates and rendered possible the emergence of efficient circulatory and
D. Atlas et al.
Proc. 13th Eur. Pept. Symp.: Peptides 1974, 361-361 (1975)
Hee-Jeong Choi et al.
Oxidative medicine and cellular longevity, 2020, 2905362-2905362 (2020-07-21)
Ultraviolet B (UVB) irradiation is major causative factor in skin aging. The aim of the present study was to investigate the protective effect of a 50% ethanol extract from Nypa fruticans (NF50E) against UVB-induced skin aging. The results indicated that
Baumstark, J.S., et al.
Biochimica et Biophysica Acta, 77, 676-676 (1963)
Chromatograms
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