Skip to Content
Merck
All Photos(1)

Key Documents

View All Documentation

1.12393

Sigma-Aldrich

Vanadium(III) chloride

99+

Synonym(s):

Vanadium(III) chloride, Vanadium trichloride

Sign Into View Organizational & Contract Pricing
All Photos(1)

About This Item

Empirical Formula (Hill Notation):
Cl3V
CAS Number:
7718-98-1
Molecular Weight:
157.30
MDL number:
MFCD00011454
UNSPSC Code:
12352302
EC Index Number:
231-744-6
NACRES:
NA.22

Quality Level

200

form

solid

potency

350 mg/kg LD50, oral (Rat)

density

3.0 g/cm3 at 20 °C

bulk density

1000 kg/m3

storage temp.

no temp limit

InChI

1S/3ClH.V/h3*1H;/q;;;+3/p-3

InChI key

HQYCOEXWFMFWLR-UHFFFAOYSA-K

Related Categories

Application

Vanadium(III) chloride (VCl3) can be used as a catalyst to synthesize:
  • Dihydropyrimidinone derivatives via a three-component Biginelli condensation reaction between aldehyde, β-keto ester, and urea (thiourea).
  • Coumarin derivatives via Pechmann condensation reaction of various phenols and β-keto esters.
  • β-amino alcohols by deprotection of epoxides with aromatic amines.
  • Diol derivatives by chemoselective cleavage of acetonides in methanol.

VCl3 can also be used as a reducing agent to determine nitrates and nitrites in water samples.

Analysis Note

Assay (complexometric): ≥ 99.0 %
Identity (ICP-OES): passes test

Pictograms

CorrosionExclamation mark
GHS05,GHS07

Signal Word

Danger

Hazard Statements

H302 - H314

Hazard Classifications

Acute Tox. 4 Oral - Eye Dam. 1 - Skin Corr. 1B

Supplementary Hazards

EUH014

Storage Class Code

8B - Non-combustible, corrosive hazardous materials

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Vanadium (III) chloride as an effective catalyst for the Pechmann reaction
Kumar BS, et al.
Chemistry of Heterocyclic Compounds, 42(2), 172-175 (2006)
Vanadium (III) chloride: A mild and efficient catalyst for the chemoselective deprotection of acetonides
Sabitha G, et al.
J. Mol. Catal. A: Chem., 238(1-2), 229-232 (2005)
Vanadium (III) chloride-catalyzed preparation of β-amino alcohols from epoxides
Sabitha G, et al.
Synthesis, 2003(15), 2298-2300 (2003)
Vanadium (III) chloride catalyzed Biginelli condensation: solution phase library generation of dihydropyrimidin-(2H)-ones
Sabitha G, et al.
Tetrahedron Letters, 44(34), 6497-6499 (2003)
Determination of nitrate plus nitrite in small volume marine water samples using vanadium (III) chloride as a reduction agent
Schnetger B and Lehners C
Marine Chemistry, 160, 91-98 (2014)

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service