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850402P

Avanti

4ME 16:0 PE

1,2-diphytanoyl-sn-glycero-3-phosphoethanolamine, powder

Synonym(s):

1,2-di-(3,7,11,15-tetramethylhexadecanoyl)-sn-glycero-3-phosphoethanolamine; PE(16:0(3me,7me,11me,15me)/16:0(3me,7me,11me,15me)), DPyPE, DphyPE

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About This Item

Empirical Formula (Hill Notation):
C45H90NO8P
CAS Number:
201036-16-0
Molecular Weight:
804.17
UNSPSC Code:
12352211
NACRES:
NA.25

Assay

>99% (TLC)

form

powder

packaging

pkg of 1 × 25 mg (850402P-25mg)

manufacturer/tradename

Avanti Research™ - A Croda Brand 850402P

shipped in

dry ice

storage temp.

−20°C

SMILES string

[H][C@@](COP([O-])(OCC[NH3+])=O)(OC(CC(C)CCCC(C)CCCC(C)CCCC(C)C)=O)COC(CC(C)CCCC(C)CCCC(C)CCCC(C)C)=O

General description

4ME 16:0 PE (1,2-diphytanoyl-sn-glycero-3-phosphoethanolamine) is a conical and neutral lipid. It is a fatty acid modified lipid. It is a phytanoyl lipid.

Application

4ME 16:0 PE (1,2-diphytanoyl-sn-glycero-3-phosphoethanolamine) may be used:
  • in the preparation of planar lipid bilayers
  • in the preparation of giant unilamellar vesicles (GUVs) for electrophysiology studies
  • to form virtually solvent-free planar lipid membranes

Biochem/physiol Actions

Diphytanoyl lipids is usually preferred as model membranes in electrophysiological experiments. Diphytanoyl phosphocholine (DPhPC) is capable of preparing oxidation-resistant, stable lipid bilayers for in vitro experiments.

Packaging

5 mL Clear Glass Sealed Ampule (850402P-25mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Storage Class Code

11 - Combustible Solids

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Anthony Yasmann et al.
Langmuir : the ACS journal of surfaces and colloids, 31(1), 350-357 (2014-12-05)
Diphytanoylphosphatidyl choline (DPhPC) is a synthetic ester lipid with methylated tails found in archaeal ether lipids. Because of the stability of DPhPC bilayers and the absence of phase transitions over a broad range of temperatures, the lipid is used as
Pratik Raj Singh et al.
The journal of physical chemistry. B, 116(15), 4433-4438 (2012-03-01)
We characterize the rate-limiting interaction of the antibiotic enrofloxacin with OmpF, a channel from the outer cell wall of Escherichia coli . Reconstitution of a single OmpF trimer into planar lipid membranes allows measurement of the ion current through
Noriko Tomita et al.
Biochimica et biophysica acta, 1828(3), 1057-1065 (2012-12-19)
Using rational membrane protein design, we were recently able to obtain a β-barrel protein nanopore that was robust under an unusually broad range of experimental circumstances. This protein nanopore was based upon the native scaffold of the bacterial ferric hydroxamate
Martin Andersson et al.
Colloids and surfaces. B, Biointerfaces, 82(2), 550-561 (2010-11-13)
Lipid bilayers are of interest in applications where a cell membrane mimicking environment is desired. The performance of the lipid bilayer is largely dependent on the physical and chemical properties of the component lipids. Lipid bilayers consisting of phytanoyl lipids
Giorgia Manzo et al.
Scientific reports, 9(1), 10934-10934 (2019-07-31)
Frogs such as Rana temporaria and Litoria aurea secrete numerous closely related antimicrobial peptides (AMPs) as an effective chemical dermal defence. Damage or penetration of the bacterial plasma membrane is considered essential for AMP activity and such properties are commonly
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