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Key Documents

M9375

Sigma-Aldrich

D-Methionine

≥98% (HPLC)

Synonym(s):

(R)-2-Amino-4-(methylmercapto)butyric acid, D-2-Amino-4-(methylthio)butanoic acid

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About This Item

Empirical Formula (Hill Notation):
C5H11NO2S
CAS Number:
Molecular Weight:
149.21
Beilstein:
1722293
EC Number:
MDL number:
UNSPSC Code:
12352209
PubChem Substance ID:
NACRES:
NA.26

Assay

≥98% (HPLC)

form

powder

color

white

mp

273 °C

application(s)

cell analysis
peptide synthesis

SMILES string

CSCC[C@@H](N)C(O)=O

InChI

1S/C5H11NO2S/c1-9-3-2-4(6)5(7)8/h4H,2-3,6H2,1H3,(H,7,8)/t4-/m1/s1

InChI key

FFEARJCKVFRZRR-SCSAIBSYSA-N

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Biochem/physiol Actions

D-methionine has been shown to rescue noise-induced hearing loss.

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Kathleen Campbell et al.
Hearing research, 282(1-2), 138-144 (2011-09-20)
We have previously reported rescue from noise-induced auditory brainstem response (ABR) threshold shifts with d-methionine (d-met) administration 1 h after noise exposure. The present study investigated further d-met rescue intervals at 3, 5 and 7 h post-noise exposure. Chinchillas laniger were exposed
Eleni Ntone et al.
Journal of colloid and interface science, 583, 459-469 (2020-10-05)
Plants offer a vast variety of protein extracts, typically containing multiple species of proteins that can serve as building blocks of soft materials, like emulsions. However, the role of each protein species concerning the formation of emulsions and interfaces with
Audrey S Vanhove et al.
Applied and environmental microbiology, 86(11) (2020-03-30)
While only a subset of Vibrio cholerae strains are human diarrheal pathogens, all are aquatic organisms. In this environment, they often persist in close association with arthropods. In the intestinal lumen of the model arthropod Drosophila melanogaster, methionine and methionine
Yi-Sin Wong et al.
Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society, 32(6), e13803-e13803 (2020-01-29)
Cisplatin is a widely used antineoplastic drug. However, cisplatin-induced dyspepsia syndromes, including delayed gastric emptying, gastric distension, early satiety, nausea, and vomiting, often force patients to take doses lower than those prescribed or even refuse treatment. D-methionine has an appetite-enhancing
Tobias Dörr et al.
PLoS genetics, 10(6), e1004433-e1004433 (2014-06-20)
The bacterial cell wall, which is comprised of a mesh of polysaccharide strands crosslinked via peptide bridges (peptidoglycan, PG), is critical for maintenance of cell shape and survival. PG assembly is mediated by a variety of Penicillin Binding Proteins (PBP)

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