M1890

rac-Glycerol 1-myristate

≥99%

• Synonym(s): 1-Monotetradecanoyl-rac-glycerol, rac-1-Myristoylglycerol, DL-α-Myristin, Monomyristin
• Linear Formula: H₃C(CH₂)₁₂COOCH₂CH(OH)CH₂OH
• CAS Number: 589-68-4
• Molecular Weight: 302.45
• Beilstein: 1727502
• MDL number: MFCD00046760
• UNSPSC Code: 12352211
• PubChem Substance ID: 24896704
• NACRES: NA.25

Properties

• biological source: synthetic (organic)
• Assay: ≥99%
• form: powder
• functional group: ester; hydroxyl
• lipid type: neutral glycerides
• shipped in: ambient
• storage temp.: −20°C
• SMILES string: CCCCCCCCCCCCCC(=O)OCC(O)CO
• InChI: 1S/C17H34O4/c1-2-3-4-5-6-7-8-9-10-11-12-13-17(20)21-15-16(19)14-18/h16,18-19H,2-15H2,1H3
• InChI key: DCBSHORRWZKAKO-UHFFFAOYSA-N

Description

General description

rac-Glycerol 1-myristate is present in the saw palmetto palm and is less soluble in water.

Application

rac-Glycerol 1-myristate has been used:

• as a standard in liquid chromatography/atmospheric-pressure chemical ionization mass spectrometry (LC–APCI-MS) studies
• as a representative monoacylglycerol to test its matrix effects in gas chromatography-mass spectrometry (GC-MS) studies
• to test its antifungal activity against Fusarium spp.

Rac-glycerol 1-myristate (glycerol α-monomyristate) is used in colloidal chemistry as a nonionic surfactant in the development of micelles.

Biochem/physiol Actions

rac-Glycerol 1-myristate also elicits antifungal activity. It exhibits an anti-proliferative effect in HeLa cervical cancer cells when delivered as a polymeric nanoparticle-based conjugate.

rac-Glycerol 1-myristate, a 1-monoglyceride of myristic acid, has antibacterial activity against several Gram-positive bacterial strains.

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves