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Olaquindox

VETRANAL®, analytical standard

Synonym(s):

N-(2-Hydroxyethyl)-3-methyl-2-quinoxalinecarboxamide 1,4-dioxide

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About This Item

Empirical Formula (Hill Notation):
C12H13N3O4
CAS Number:
23696-28-8
Molecular Weight:
263.25
EC Number:
245-832-7
MDL number:
MFCD00210341
UNSPSC Code:
41116107
PubChem Substance ID:
329754726
NACRES:
NA.24

grade

analytical standard

Quality Level

100

product line

VETRANAL®

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

forensics and toxicology
pharmaceutical (small molecule)

format

neat

SMILES string

Cc1c(C(=O)NCCO)[n+]([O-])c2ccccc2[n+]1[O-]

InChI

1S/C12H13N3O4/c1-8-11(12(17)13-6-7-16)15(19)10-5-3-2-4-9(10)14(8)18/h2-5,16H,6-7H2,1H3,(H,13,17)

InChI key

TURHTASYUMWZCC-UHFFFAOYSA-N

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General description

Olaquindox is an antibiotic veterinary drug, used as a growth promoter for pig farming.

Application

Olaquindox may be used as a reference standard in the determination of olaquindox in feed samples using matrix solid-phase dispersion extraction (MSPDE) and hydrophilic interaction ultra-high-pressure liquid chromatography (HILIC-UHPLC) with photodiode array detector.
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

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Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.

Legal Information

VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

Pictograms

Health hazardExclamation mark
GHS08,GHS07

Signal Word

Danger

Hazard Statements

H302,H334

Hazard Classifications

Acute Tox. 4 Oral - Resp. Sens. 1

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
BCCH1618
BCBW1743
SZBD099XV
SZBA074XV
SZBA074X

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Wentao Guo et al.
PloS one, 7(8), e43322-e43322 (2012-09-07)
Quinoxaline 1, 4-dioxides (QdNOs) has been used in animals as antimicrobial agents and growth promoters for decades. However, the resistance to QdNOs in pathogenic bacteria raises worldwide concern but it is barely known. To explore the molecular mechanism involved in
Zhao-Ying Liu et al.
Toxicology letters, 200(1-2), 24-33 (2010-10-27)
Olaquindox is a growth-promoting feed additive for food-producing animals. Its toxicities were reported to be closely related to the metabolism. To provide the interpretation of toxicities in animals, this study explored the metabolism of olaquindox in rats, chickens and pigs
Tianci Xu et al.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 50(7), 2540-2546 (2012-04-25)
The interaction between olaquindox (OLA) and bovine serum albumin (BSA) was investigated using fluorescence, UV-vis absorption and circular dichroism (CD) spectroscopy. The results showed that the fluorescence quenching of BSA by OLA was a static quenching process induced by the
Biodegradability of metronidazole, olaquindox, and tylosin and formation of tylosin degradation products in aerobic soil--manure slurries
Ingerslev F and Halling-Sorensen B
Ecotoxicology and Environmental Safety, 48(3), 311-320 (2001)
Xian-Ju Huang et al.
Chemico-biological interactions, 185(3), 227-234 (2010-03-02)
Quinoxaline 1,4-dioxides (QdNOs) derivatives, the potent synthetic antibacterial group used in food-producing animals, are assumed to have pro-oxidant properties. However, how oxidative stress mediated their adrenal toxicity is far from clear. The aim of this study was to assess the
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