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Key Documents

12115

Sigma-Aldrich

Benzidine

purum p.a., ≥98.0% (N)

Synonym(s):

4,4′-Diaminobiphenyl

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About This Item

Empirical Formula (Hill Notation):
C12H12N2
CAS Number:
Molecular Weight:
184.24
Beilstein:
742770
EC Number:
MDL number:
UNSPSC Code:
12352116
PubChem Substance ID:
NACRES:
NA.25

grade

purum p.a.

Quality Level

Assay

≥98.0% (N)

SMILES string

Nc1ccc(cc1)-c2ccc(N)cc2

InChI

1S/C12H12N2/c13-11-5-1-9(2-6-11)10-3-7-12(14)8-4-10/h1-8H,13-14H2

InChI key

HFACYLZERDEVSX-UHFFFAOYSA-N

Gene Information

human ... UGT1A4(54657)

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Application

Benzidine can be used to study bioactive small molecules and cell biology. Benzidine has been used to determine pollen viability and stigma receptivity of Angelica dahurica. Benzidine has also been used to study cross-linking of horseradish peroxidase adsorbed on polycationic films.
for spectrophotometric determination of CN-, NO2-, ClO3-, SO42-

Other Notes

Reagent for the det. of blood; Reagent for the det. of peroxidases.; Reagent for the spectrophotometric det. of CN-, NO2-, ClO3-, etc.
Sales restrictions may apply

Signal Word

Danger

Hazard Statements

Hazard Classifications

Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Carc. 1A

Storage Class Code

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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J.L. Royer et al.
Analytical Letters, 6, 619-619 (1973)
E.A. Burns
Analytical Chemistry, 32, 1800-1800 (1960)
THE BENZIDINE TEST: A CRITICAL REVIEW.
B J CULLIFORD et al.
Journal of forensic sciences, 9(1), 175-191 (1964-01-01)
Brian J Pak et al.
PLoS neglected tropical diseases, 8(8), e3002-e3002 (2014-08-08)
Strongyloidiasis is a persistent human parasitic infection caused by the intestinal nematode, Strongyloides stercoralis. The parasite has a world-wide distribution, particularly in tropical and subtropical regions with poor sanitary conditions. Since individuals with strongyloidiasis are typically asymptomatic, the infection can
J Whysner et al.
Pharmacology & therapeutics, 71(1-2), 107-126 (1996-01-01)
The aromatic amine benzidine (BZ) has produced various tumors, including liver tumors, in mice, rats and hamsters. BZ forms DNA adducts in rodent liver, and it is positive in most genotoxicity tests. Only bladder tumors are produced in dogs and

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