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103624

Sigma-Aldrich

Sudan I

Dye content ≥95 %

Synonym(s):

1-Phenylazo-2-naphthol, Solvent Yellow 14

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About This Item

Linear Formula:
C6H5N=NC10H6OH
CAS Number:
Molecular Weight:
248.28
Colour Index Number:
12055
EC Number:
MDL number:
UNSPSC Code:
12171500
PubChem Substance ID:
NACRES:
NA.47

form

powder

Quality Level

composition

Dye content, ≥95%

color

orange to very dark orange

pH

10.2 (26 °C)

mp

131-133 °C (lit.)

solubility

chloroform: 1 mg/mL, clear to very slightly hazy, orange

density

0.32 g/cm3 at 20 °C ((68 °F) - OECD Test Guideline 109)

ε (extinction coefficient)

≥30000 at 223-233 nm in ethanol at 0.01 g/L

εmax

≥6000 at 299-319 nm in ethanol at 0.01 g/L (2nd)

λmax

≥11000 at 461-491 nm in ethanol at 0.01 g/L

application(s)

diagnostic assay manufacturing
hematology
histology

storage temp.

room temp

SMILES string

Oc1ccc2ccccc2c1N=Nc3ccccc3

InChI

1S/C16H12N2O/c19-15-11-10-12-6-4-5-9-14(12)16(15)18-17-13-7-2-1-3-8-13/h1-11,19H

InChI key

MRQIXHXHHPWVIL-UHFFFAOYSA-N

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Application

Sudan I is a lysochrome, a diazo-conjugate dye, used as an industrial dye, added to products such as waxes, oils, petrol, solvents and polishes. Sudan I is a category 3 carcinogen previously, now banned, used to color certain foodstuffs.

Pictograms

Health hazardExclamation mark

Signal Word

Warning

Hazard Statements

Hazard Classifications

Aquatic Chronic 4 - Carc. 2 - Muta. 2 - Skin Sens. 1

Storage Class Code

11 - Combustible Solids

WGK

WGK 2

Flash Point(F)

>554.0 °F - Pensky-Martens closed cup

Flash Point(C)

> 290 °C - Pensky-Martens closed cup


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T Philip et al.
Journal of chromatography, 435(1), 113-126 (1988-01-01)
The adsorption and partition properties of several fatty acid esters of capsanthin, capsorubin, beta-cryptoxanthin, lutein, violaxanthin and beta-citraurin isolated from fruits were studied by normal-phase (silica) and reversed-phase (octadecylsilane) liquid chromatography using Sudan 1 as internal standard. The separation on
Michalina Oplatowska et al.
Analytical and bioanalytical chemistry, 401(4), 1411-1422 (2011-07-07)
Sudan dyes have been found to be added to chilli and chilli products for illegal colour enhancement purposes. Due to the possible carcinogenic effect, they are not authorized to be used in food in the European Union or the USA.
Myriam Coulet et al.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 48 Suppl 1, S106-S111 (2010-02-02)
Sudan I is generally considered mutagenic based on various in vitro and in vivo tests and is carcinogenic in the rat. Dose-response modelling of the data for hepatocellular adenomas in male rats gave a BMDL(10) of 7.3mg/kg-bw/day. Sudan I is
Marie Stiborová et al.
Chemical research in toxicology, 26(2), 290-299 (2013-01-08)
Sudan I (1-phenylazo-2-hydroxynaphthol) is a suspected human carcinogen causing tumors in the livers and urinary bladders of rats, mice, and rabbits. Here, we investigated for the first time the influence of Sudan I exposure on the expression of several biotransformation
George E Johnson et al.
Mutagenesis, 25(4), 327-333 (2010-03-04)
Sudan-1 and para red are industrial dyes that have been illegally added to some foodstuffs, leading to withdrawal of the adulterated products throughout the UK since 2003. This resulted in international concern that arose because Sudan-1 is classified by International

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