I3875
Indoxyl sulfate potassium salt
Synonym(s):
Potassium 3-indoxyl sulfate, Urinary indican
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About This Item
Linear Formula:
C8H6NO4SK
CAS Number:
Molecular Weight:
251.30
Beilstein:
3921324
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22
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Assay
> 98 %
Quality Level
mp
165 °C (dec.) (lit.)
solubility
water: soluble
storage temp.
−20°C
SMILES string
[K+].[O-]S(=O)(=O)Oc1c[nH]c2ccccc12
InChI
1S/C8H7NO4S.K/c10-14(11,12)13-8-5-9-7-4-2-1-3-6(7)8;/h1-5,9H,(H,10,11,12);/q;+1/p-1
InChI key
MDAWATNFDJIBBD-UHFFFAOYSA-M
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Related Categories
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Product No.
Description
Pricing
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
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Binding affinity and capacity for the uremic toxin indoxyl sulfate
Devine, et al.
Toxins, 6, 416-429 (2014)
Bummei Sato et al.
The American journal of cardiology, 111(5), 712-716 (2012-12-12)
The prognosis of patients with diastolic heart failure (HF) is as poor as that of patients with systolic HF. Greater chronic kidney disease-associated mortality occurs in patients with left ventricular (LV) diastolic HF than in those with systolic HF. Indoxyl
Indoxyl-sulfate activation of the AhR-NF-$\kappa$B pathway promotes interleukin-6 secretion and the subsequent osteogenic differentiation of human valvular interstitial cells from the aortic valve
Candellier, et al.
Journal of Molecular and Cellular Cardiology, 179, 18-29 (2023)
Carel J Pretorius et al.
Clinica chimica acta; international journal of clinical chemistry, 419, 122-126 (2013-02-23)
The uremic toxins indoxyl sulphate (IS) and p-cresyl sulphate (pCS) are absorbed bacterial metabolites of tryptophan and tyrosine respectively and may be predictive of clinical outcome. Long chromatography times, incomplete data on the reference ranges of the free and total
Indoxyl sulfate upregulates liver P-glycoprotein expression and activity through aryl hydrocarbon receptor signaling
Machado, et al.
Journal of the American Society of Nephrology, 29, 906-918 (2018)
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