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149861

Sigma-Aldrich

2-Furoyl chloride

95%

Synonym(s):

Furan-2-carbonyl chloride

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About This Item

Empirical Formula (Hill Notation):
C5H3ClO2
CAS Number:
527-69-5
Molecular Weight:
130.53
Beilstein:
110144
EC Number:
208-422-9
MDL number:
MFCD00003228
UNSPSC Code:
12352100
PubChem Substance ID:
24848981
NACRES:
NA.22

Assay

95%

form

liquid

refractive index

n20/D 1.531 (lit.)

bp

173-174 °C (lit.)

mp

−2 °C (lit.)

density

1.324 g/mL at 25 °C (lit.)

SMILES string

ClC(=O)c1ccco1

InChI

1S/C5H3ClO2/c6-5(7)4-2-1-3-8-4/h1-3H

InChI key

OFTKFKYVSBNYEC-UHFFFAOYSA-N

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Application

2-Furoyl chloride is used in the chararcterisation of mixtures of polyethoxylated alcohols and their sulphates. It was also used in the preparation of S-2-furoyl-O-alkyldithiocarbonic anhydrides.

Pictograms

CorrosionExclamation mark
GHS05,GHS07

Signal Word

Danger

Hazard Statements

H302 + H312 + H332,H314

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Dam. 1 - Skin Corr. 1B

Storage Class Code

8A - Combustible corrosive hazardous materials

WGK

WGK 3

Flash Point(F)

185.0 °F - closed cup

Flash Point(C)

85 °C - closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Julien Morvan et al.
Analytical and bioanalytical chemistry, 384(6), 1409-1415 (2006-02-28)
Bachus et al. [1] recently described a new derivatisation method using 2-furoyl chloride for the characterisation of mixtures of polyethoxylated alcohols and their corresponding sulfates. This paper deals with the control of the derivatisation steps; hydrolysis and extraction conditions were
Ethel A Wilhelm et al.
Canadian journal of physiology and pharmacology, 98(5), 304-313 (2019-12-11)
The present study evaluated the in vitro acetylcholinesterase (AChE) inhibitor activity of two new selanyl amide derivatives in cerebral structures of mice. Our results demonstrated that N-(2-(3-(phenylselanyl)propoxy)phenyl)furan-2-carboxamide (1) and N-(2-(3-(phenylselanyl)propoxy)phenyl)thiophene-2-carboxamide (2) inhibited the in vitro AChE activity in mice. Another
J Tułecki et al.
Polish journal of pharmacology and pharmacy, 37(5), 709-715 (1985-09-01)
New S-2-furoyl-O-alkyldithiocarbonic anhydrides have been obtained by condensation of 2-furoyl chloride with potassium O-alkyl-dithiocarbonates. The toxicity and radiosensitizing activity of these compounds were determined.
Christoph Cerny et al.
Food chemistry, 337, 128008-128008 (2020-09-14)
This study investigated the role of furfuryl alcohol (FFA) in the formation of furfurylthiol (FFT), the most important odorant in roasted coffee, using in-bean and spiking experiments. Green beans were spiked with FFA, and after roasting FFT was quantified by
Won-Ji Lee et al.
Polymers, 12(3) (2020-03-12)
In this paper, a self-healable nanocomposite based on the Diels-Alder reaction is developed. A graphene-based nanofiller is introduced to improve the self-healing efficiency, as well as the mechanical properties of the nanocomposite. Graphene oxide (GO) is modified with maleimide functional
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