860720P
Avanti
Lyso iGB3 (synthetic)
powder
Synonym(s):
Isoglobotriaosylsphingosine
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About This Item
Empirical Formula (Hill Notation):
C36H67NO17
CAS Number:
Molecular Weight:
785.91
UNSPSC Code:
12352211
NACRES:
NA.25
Recommended Products
Assay
99% (TLC)
form
powder
packaging
package of 1 × 500 μg (860720P-500UG)
manufacturer/tradename
Avanti Research™ - A Croda Brand
lipid type
sphingolipids
shipped in
dry ice
storage temp.
−20°C
General description
Isoglobotriaosylsphingosine (Lyso iGB3) is a truncated form of iGb3. It is a β-linked glycolipid. Isogloboside 3 (iGb3) is a glycosphingolipid.
Biochem/physiol Actions
Isogloboside 3 (iGb3) acts as an endogenous ligand for natural killer T (NKT) cells.
Packaging
5 mL Amber Glass Screw Cap Vial (860720P-500UG)
Legal Information
Avanti Research is a trademark of Avanti Polar Lipids, LLC
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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Find documentation for the products that you have recently purchased in the Document Library.
Synthesis and biological evaluation of alpha-galactosylceramide (KRN7000) and isoglobotrihexosylceramide (iGb3)
Xia C, et al.
Bioorganic & Medicinal Chemistry Letters, 16(8), 2195-2199 (2006)
Humans lack iGb3 due to the absence of functional iGb3-synthase: implications for NKT cell development and transplantation
Christiansen D, et al.
PLoS Biology, 6(7) (2008)
Psychosine variants as antigens for natural killer T cells
Deng S, et al.
Chemical Science, 8(3), 2204-2208 (2017)
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