A substrate-unspecified glycosylation reaction promoted by copper(II) trifluoromethanesulfonate in benzotrifluoride.

A substrate-unspecified glycosylation reaction promoted by copper(II) trifluoromethanesulfonate in benzotrifluoride.

Carbohydrate research (2002-03-23)

Hidetoshi Yamada, Tomomi Hayashi

PMID11909590

ABSTRACT

A glycosylation reaction induced by copper(II) trifluoromethanesulfonate is described. Using benzotrifluoride as the reaction solvent, five kinds of glycosyl donors, a glucosyl chloride, a fluoride, a trichloroacetimidate, a 1-O-acetyl compound, and a lactol were activated to give the corresponding glucosides.

MATERIALS

Product Number

Brand

Product Description

547948

Sigma-Aldrich

α,α,α-Trifluorotoluene, anhydrous, ≥99%

T63703

Sigma-Aldrich

α,α,α-Trifluorotoluene, ≥99%

551406

Sigma-Aldrich

α,α,α-Trifluorotoluene solution, NMR reference standard, 0.05% in benzene-d₆ (99.6 atom % D)

612685

Sigma-Aldrich

α,α,α-Trifluorotoluene solution, NMR reference standard, 0.05% in benzene-d₆ (99.6 atom % D), NMR tube size 3 mm × 8 in.

733806

Sigma-Aldrich

α,α,α-Trifluorotoluene solution, NMR reference standard, 0.05% in benzene-d₆ (99.6 atom % D), NMR tube size 10 mm × 8 in.