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913375

Sigma-Aldrich

Branched polyethylenimine solution

2mg/mL aqueous solution, suitable for biomedical research

Synonym(s):

PEI solution

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About This Item

Linear Formula:
H(NHCH2CH2)mNH2
CAS Number:
9002-98-6
UNSPSC Code:
12352116
NACRES:
NA.23

Quality Level

100

form

liquid

concentration

2 mg/mL

color

colorless to pale yellow

storage temp.

2-8°C

InChI

1S/C2H5N/c1-2-3-1/h3H,1-2H2

InChI key

NOWKCMXCCJGMRR-UHFFFAOYSA-N

Related Categories

Application

High molecular weight branched PEI is commonly used in gene delivery due to its high transfection efficiency in a broad range of cells. Branched PEI has been used to successfully deliver genetic material both in vitro and in vivo, while maintaining low cytotoxicity with DNA complexation.

Storage Class Code

12 - Non Combustible Liquids

WGK

WGK 1

Certificates of Analysis (COA)

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O Boussif et al.
Proceedings of the National Academy of Sciences of the United States of America, 92(16), 7297-7301 (1995-08-01)
Several polycations possessing substantial buffering capacity below physiological pH, such as lipopolyamines and polyamidoamine polymers, are efficient transfection agents per se--i.e., without the addition of cell targeting or membrane-disruption agents. This observation led us to test the cationic polymer polyethylenimine
W T Godbey et al.
Journal of biomedical materials research, 45(3), 268-275 (1999-07-09)
Poly(ethylenimine) (PEI) samples of various molecular weights and pHs were used to transfect endothelial cells to achieve levels of gene expression for comparison. PEIs with nominal molecular weights of 600, 1200, 1800, 10,000, and 70,000 Da were examined at pHs

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