- Improved synthesis of a DNA-dependent protein kinase inhibitor IC86621.
Improved synthesis of a DNA-dependent protein kinase inhibitor IC86621.
Archives of pharmacal research (2012-05-04)
Girish Chandra, Varughese Alexander, Hyuk Woo Lee, Lak Shin Jeong
PMID22553056
RESUMO
An improved synthesis of DNA-dependent protein kinase inhibitor, IC86621 is described. This developed method provides an easy access to this simple molecule by using amination, acetylation and Fries rearrangement reactions.
MATERIAIS