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Documentos Principais

U3128

Sigma-Aldrich

Uroporphyrin I dihydrochloride

≥95%

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About This Item

Fórmula empírica (Notação de Hill):
C40H38N4O16 · 2HCl
Número CAS:
Peso molecular:
903.67
Número CE:
Número MDL:
Código UNSPSC:
12352300
ID de substância PubChem:
NACRES:
NA.22

Ensaio

≥95%

Formulário

powder

adequação da reação

core: porphyrin
reagent type: catalyst

temperatura de armazenamento

−20°C

cadeia de caracteres SMILES

Cl.Cl.OC(=O)CCc1c(CC(O)=O)c2cc3[nH]c(cc4nc(cc5[nH]c(cc1n2)c(CC(O)=O)c5CCC(O)=O)c(CC(O)=O)c4CCC(O)=O)c(CC(O)=O)c3CCC(O)=O

InChI

1S/C40H38N4O16.2ClH/c45-33(46)5-1-17-21(9-37(53)54)29-14-26-19(3-7-35(49)50)23(11-39(57)58)31(43-26)16-28-20(4-8-36(51)52)24(12-40(59)60)32(44-28)15-27-18(2-6-34(47)48)22(10-38(55)56)30(42-27)13-25(17)41-29;;/h13-16,41,44H,1-12H2,(H,45,46)(H,47,48)(H,49,50)(H,51,52)(H,53,54)(H,55,56)(H,57,58)(H,59,60);2*1H/b25-13-,26-14-,27-15-,28-16-,29-14-,30-13-,31-16-,32-15-;;

chave InChI

DZLKLVAJOHLPKP-ARSPAUKVSA-N

Nota de preparo

Enzymatically prepared

Código de classe de armazenamento

11 - Combustible Solids

Classe de risco de água (WGK)

WGK 3

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable


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S G Afonso et al.
Journal of enzyme inhibition, 10(2), 141-146 (1996-01-01)
The effect of uroporphyrin I (UI) on several cytosolic and mitochondrial enzymes (succinyl CoA synthetase, delta-aminolevulinic acid synthetase, rhodanese, lactate dehydrogenase) has been examined. All the enzymes were inactivated in the presence of the porphyrin both in the dark and
S G Afonso et al.
Journal of enzyme inhibition, 5(3), 225-233 (1991-01-01)
The action of uroporphyrin I (URO I) on the activity of red cell uroporphyrinogen decarboxylase (URO-D) in the dark and under UV light was studied. Light-dependent-and light-independent inactivation was observed. Both effects increased at increasing concentrations of URO I, the
S Afonso et al.
The international journal of biochemistry & cell biology, 30(4), 535-543 (1998-07-24)
Uroporphyrin and protoporphyrin produce alterations on 5-aminolevulinic acid dehydratase and porphobilinogen deaminase, as a result of a direct effect of porphyrins on the protein structure. With the aim of assessing the possible protection from the porphyrins effect on the proteins
Simon Y L Ching et al.
Analytical biochemistry, 353(2), 257-265 (2006-03-28)
Few methods for assessing total antioxidant capacity (TAC) include both the percentage of inhibition and the length of inhibition in the measurement. Available methods require above ambient constant temperature incubation, reaction preheating, and/or separate assays for testing hydrophilic and hydrophobic
K M Morehouse et al.
Archives of biochemistry and biophysics, 283(2), 306-310 (1990-12-01)
The anaerobic enzymatic one-electron reduction of uroporphyrin I (in the absence of light) by the ferredoxin/ferredoxin:NADP+ oxidoreductase system was investigated using NADPH as the source of reducing equivalents. The porphyrin anion free radical metabolite formed by one-electron reduction of the

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