SAB5701798

Anti-Phospho-PFKFB2-S483 antibody produced in rabbit

• Código UNSPSC: 12352203
• NACRES: NA.41

Propriedades

• fonte biológica: rabbit
• Nível de qualidade: 100
• tipo de produto de anticorpo: primary antibodies
• clone: polyclonal
• forma: liquid
• reatividade de espécies: rat, mouse, human
• concentração: 1.44 mg/mL
• técnica(s): western blot: 1:500-1:2000
• nº de adesão UniProt: O60825
• Condições de expedição: wet ice
• temperatura de armazenamento: −20°C
• modificação pós-traducional do alvo: phosphorylation (pSer483)
• Informações sobre genes: human ... PFKFB2(5208)

Descrição

Descrição geral

The protein encoded by this gene is involved in both the synthesis and degradation of fructose-2,6-bisphosphate, a regulatory molecule that controls glycolysis in eukaryotes. The encoded protein has a 6-phosphofructo-2-kinase activity that catalyzes the synthesis of fructose-2,6-bisphosphate, and a fructose-2,6-biphosphatase activity that catalyzes the degradation of fructose-2,6-bisphosphate. This protein regulates fructose-2,6-bisphosphate levels in the heart, while a related enzyme encoded by a different gene regulates fructose-2,6-bisphosphate levels in the liver and muscle. This enzyme functions as a homodimer. Two transcript variants encoding two different isoforms have been found for this gene.

Imunogênio

A synthetic phosphorylated peptide around S483 of human PFKFB2 (NP_006203.2).

forma física

Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.

Informações de segurança

• Código de classe de armazenamento: 12 - Non Combustible Liquids
• Classe de risco de água (WGK): WGK 1
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable