SAB5700111

Anti-PDCD10 antibody produced in rabbit

• Sinônimo(s): CCM3, PDCD10, TFAR15
• Código UNSPSC: 12352203
• NACRES: NA.41
• clone: polyclonal
• application: IF; WB
• reatividade de espécies: human, mouse
• técnica(s): immunofluorescence: 1:50-1:200; western blot: 1:200-1:2000

Propriedades

• fonte biológica: rabbit
• Nível de qualidade: 100
• forma do anticorpo: affinity isolated antibody
• tipo de produto de anticorpo: primary antibodies
• clone: polyclonal
• Formulário: buffered aqueous solution
• peso molecular: 24
• reatividade de espécies: human, mouse
• concentração: 1.82 mg/ml
• técnica(s): immunofluorescence: 1:50-1:200; western blot: 1:200-1:2000
• nº de adesão UniProt: Q9BUL8
• Condições de expedição: wet ice
• temperatura de armazenamento: −20°C
• modificação pós-traducional do alvo: unmodified
• Informações sobre genes: human ... PDCD10(11235)

Descrição

Descrição geral

This gene encodes an evolutionarily conserved protein associated with cell apoptosis. The protein interacts with the serine/threonine protein kinase MST4 to modulate the extracellular signal-regulated kinase (ERK) pathway. It also interacts with and is phosphoryated by serine/threonine kinase 25, and is thought to function in a signaling pathway essential for vascular developent. Mutations in this gene are one cause of cerebral cavernous malformations, which are vascular malformations that cause seizures and cerebral hemorrhages. Multiple alternatively spliced variants, encoding the same protein, have been identified.

Imunogênio

Recombinant fusion protein containing a sequence corresponding to amino acids 1-212 of human PDCD10 (NP_009148.2).

forma física

PBS with 0.02% sodium azide,50% glycerol,pH7.3.

Armazenamento e estabilidade

Store at -20℃. Avoid freeze / thaw cycles.

Informações de segurança

• Código de classe de armazenamento: 12 - Non Combustible Liquids
• Classe de risco de água (WGK): WGK 1
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable