SAB5300394

Monoclonal Anti-PTK2B antibody produced in mouse

clone 5E2D5, ascites fluid

• Sinônimo(s): CAKB, FAK2, FRNK, PKB, PTK
• Código UNSPSC: 12352203
• NACRES: NA.41

Propriedades

• fonte biológica: mouse
• conjugado: unconjugated
• forma do anticorpo: ascites fluid
• tipo de produto de anticorpo: primary antibodies
• clone: 5E2D5, monoclonal
• peso molecular: 115.8 kDa
• reatividade de espécies: human
• técnica(s): direct ELISA: 1:10,000; immunohistochemistry: 1:200-1:1,000; western blot: 1:500-1:2,000
• Isotipo: IgG2a
• nº de adesão NCBI: NM_173174
• Condições de expedição: wet ice
• temperatura de armazenamento: −20°C
• modificação pós-traducional do alvo: unmodified
• Informações sobre genes: human ... PYK2(2185)

Descrição

Descrição geral

Protein tyrosine kinase 2 β (PTK2B) is a member of the focal adhesion kinase family which is expressed in the brain. The gene encoding it is localized on human chromosome 8.

Imunogênio

Purified recombinant fragment of PYK2 (aa815-997) expressed in E.coli.
Mouse monoclonal antibody raised against PYK2

Ações bioquímicas/fisiológicas

Protein tyrosine kinase 2 β (PTK2B) takes part in the β2-mediated signaling pathway and activates mitogen activated protein kinase pathway. The protein has been shown to be upregulated in many tumors. PTK2B also has a role in cell proliferation and migration. It regulates ion channels which are induced by calcium.

forma física

Ascitic fluid containing 0.03% sodium azide.

Exoneração de responsabilidade

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Informações de segurança

• Código de classe de armazenamento: 10 - Combustible liquids
• Classe de risco de água (WGK): WGK 3
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable