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SAB3501074

Sigma-Aldrich

Anti-DNM1L antibody produced in rabbit

affinity isolated antibody

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100 μG
R$ 1.967,00

R$ 1.967,00

Previsão de entrega em23 de abril de 2025

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100 μG
R$ 1.967,00

About This Item

Código UNSPSC:
12352203
NACRES:
NA.41

R$ 1.967,00

Previsão de entrega em23 de abril de 2025

fonte biológica

rabbit

Nível de qualidade

100

conjugado

unconjugated

forma do anticorpo

affinity isolated antibody

tipo de produto de anticorpo

primary antibodies

clone

polyclonal

Formulário

buffered aqueous solution

peso molecular

predicted mol wt 81 kDa

reatividade de espécies

mouse, human

concentração

1 mg/mL

técnica(s)

ELISA: suitable
immunoblotting: suitable
immunocytochemistry: suitable
immunofluorescence: suitable

nº de adesão NCBI

NP_036192

nº de adesão UniProt

O00429

Condições de expedição

wet ice

temperatura de armazenamento

−20°C

Informações sobre genes

human ... DNM1L(10059)

Imunogênio

Antibody was raised against a 19 amino acid peptide near the center of human DNM1L.

Características e benefícios

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Ligação

The action of this antibody can be blocked using blocking peptide SBP3501074.

forma física

Supplied at 1 mg/mL in PBS with 0.02% sodim azide.

Exoneração de responsabilidade

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Código de classe de armazenamento

10 - Combustible liquids

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable

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Certificados de análise (COA)

Lot/Batch Number

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S Frank et al.
Developmental cell, 1(4), 515-525 (2001-11-13)
In healthy cells, fusion and fission events participate in regulating mitochondrial morphology. Disintegration of the mitochondrial reticulum into multiple punctiform organelles during apoptosis led us to examine the role of Drp1, a dynamin-related protein that mediates outer mitochondrial membrane fission.
P Hemachandra Reddy et al.
Brain research reviews, 67(1-2), 103-118 (2010-12-15)
The purpose of this article is to review the recent developments of abnormal mitochondrial dynamics, mitochondrial fragmentation, and neuronal damage in neurodegenerative diseases, including Alzheimer's, Parkinson's, Huntington's, and amyotrophic lateral sclerosis. The GTPase family of proteins, including fission proteins, dynamin
H W Shin et al.
Journal of biochemistry, 122(3), 525-530 (1997-11-05)
The dynamin family of GTP-binding proteins are implicated in vesicular transport. These include mammalian dynamins I, II, III, and yeast Vps1p and Dnm1p. Dynamin is involved in the formation of clathrin-coated vesicles at the plasma membrane. On the other hand
Carola Stockburger et al.
Journal of Alzheimer's disease : JAD, 42(2), 395-411 (2014-06-06)
Recent data suggest that the combined effect of oxidative stress due to aging and slightly elevated amyloid-β (Aβ) levels initiate Alzheimer's disease (AD) long before the clinical onset. Investigations of this early phase are hampered by the lack of cellular
Mabel Lum et al.
International journal of medical microbiology : IJMM, 304(5-6), 530-541 (2014-04-24)
Shigella infection in epithelial cells induces cell death which is accompanied by mitochondrial dysfunction. In this study the role of the mitochondrial fission protein, Drp1 during Shigella infection in HeLa cells was examined. Significant lactate dehydrogenase (LDH) release was detected

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