SAB2501651

Anti-CREB3L1 (C-terminal) antibody produced in goat

affinity isolated antibody, buffered aqueous solution

• Sinônimo(s): BBF-2 (Drosophila) homolog, CAMP responsive element binding protein 3-like 1, Old astrocyte specifically induced substance
• Código UNSPSC: 12352203
• NACRES: NA.41

Propriedades

• fonte biológica: goat
• conjugado: unconjugated
• forma do anticorpo: affinity isolated antibody
• tipo de produto de anticorpo: primary antibodies
• clone: polyclonal
• forma: buffered aqueous solution
• reatividade de espécies: human
• técnica(s): indirect ELISA: suitable; western blot: suitable
• nº de adesão UniProt: Q96BA8
• Condições de expedição: dry ice
• temperatura de armazenamento: −20°C
• modificação pós-traducional do alvo: unmodified
• Informações sobre genes: human ... CREB3L1(90993)

Descrição

Descrição geral

Cyclic AMP-responsive element-binding protein 3-like protein 1 (CREB3L1) belongs to the CREB family of transcription factors. It has a bZIP (basic-leucine zipper) domain and a DNA binding domain. The gene encoding this protein is mapped to human chromosome 11 and is expressed in many tissues.

Imunogênio

Peptide with sequence DFSHSKEWFHDRD, from the C-terminal region of the protein sequence according to NP_443086.1

Ações bioquímicas/fisiológicas

Cyclic AMP-responsive element-binding protein 3-like protein 1 (CREB3L1) is an unfolded protein response (UPR) transducer. It localizes in the endoplasmic reticulum. In the presence of UPR signaling, CREB3L1 is cleaved and the amino terminal part is translocated to the nucleus. The nuclear part regulates target gene expression. CREB3L1 is involved in the differentiation and development of astrocytes, osteoblasts, odontoblasts, pancreatic beta-cells and large intestine goblet cells.

Características e benefícios

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forma física

Supplied at 0.5 mg/mL in 20mM Tris (pH 7.3) and 150mM NaCl with 0.02% sodium azide and 0.5% bovine serum albumin.

Informações de segurança

• Código de classe de armazenamento: 10 - Combustible liquids
• Classe de risco de água (WGK): WGK 2
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable