Pular para o conteúdo
Merck
Todas as fotos(1)

Documentos Principais

Visualizar Toda a Documentação

K2380

Sigma-Aldrich

D-Kynurenine

Sinônimo(s):

β-Anthraniloyl-D-alanine, D-2-Amino-4-(2-aminophenyl)-4-oxobutanoic acid

Faça loginpara ver os preços organizacionais e de contrato
Todas as fotos(1)

About This Item

Fórmula empírica (Notação de Hill):
C10H12N2O3
Número CAS:
13441-51-5
Peso molecular:
208.21
Número MDL:
MFCD00133224
Código UNSPSC:
12352202
ID de substância PubChem:
24896220
NACRES:
NA.26

Ensaio

≥98% (TLC)

forma

powder

técnica(s)

ligand binding assay: suitable

cor

faint yellow to yellow

aplicação(ões)

cell analysis

cadeia de caracteres SMILES

N[C@H](CC(=O)c1ccccc1N)C(O)=O

InChI

1S/C10H12N2O3/c11-7-4-2-1-3-6(7)9(13)5-8(12)10(14)15/h1-4,8H,5,11-12H2,(H,14,15)/t8-/m1/s1

chave InChI

YGPSJZOEDVAXAB-MRVPVSSYSA-N

Ações bioquímicas/fisiológicas

D-Kynurenine may be used along with L-kynurenine to assess the specificity and kinetics of kynurenine metabolizing enzymes. D-Kynurenine is used to study the selectivity and activity of the G protein-coupled receptor, GPR109B. D-Kynurenine is used as a substrate in a fluorometric assay of D-amino acid oxidase.

Código de classe de armazenamento

11 - Combustible Solids

Classe de risco de água (WGK)

WGK 3

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable

Equipamento de proteção individual

Eyeshields, Gloves, type N95 (US)

Certificados de análise (COA)

Busque Certificados de análise (COA) digitando o Número do Lote do produto. Os números de lote e remessa podem ser encontrados no rótulo de um produto após a palavra “Lot” ou “Batch”.

Já possui este produto?

Encontre a documentação dos produtos que você adquiriu recentemente na biblioteca de documentos.

Visite a Biblioteca de Documentos

Masato Hoshi et al.
Toxicology, 438, 152458-152458 (2020-04-15)
Kynurenine (Kyn) plays an important role as an immune check-point molecule and regulates various immune responses through its aryl hydrocarbon receptor (Ahr). Kyn is synthesized by indoleamine 2,3-dioxygenase (Ido) and tryptophan 2,3-dioxygenase (Tdo). Ido contributes approximately 90% of tryptophan catabolism.
Sumiko Iwasa et al.
Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan, 131(7), 1111-1116 (2011-07-02)
A facile fluorometric assay using D-kynurenine as a substrate was utilized for evaluating the inhibition of D-amino acid oxidase (DAAO), which is one of the products of a susceptibility gene for schizophrenia, by commercial antipsychotic drugs, namely, chlorpromazine (CPZ), carbamazepine
Kana Ishii et al.
Chirality, 22(10), 901-906 (2010-09-28)
An aqueous solution of enantiomerically pure tryptophan (Trp), namely, D-Trp or L-Trp (100 mg/kg), was administered intraperitoneally to male Sprague-Dawley rats. The time-course profiles of the rat plasma concentrations of D-kynurenine (KYN), L-KYN, and kynurenic acid (KYNA), which are metabolites
Aysha Sarfraz Rizvi et al.
Journal of chromatography. A, 1622, 461128-461128 (2020-04-26)
We present high resolution fast, cost-effective and sensitive Capillary zone electrophoresis (CZE) methods for determination of enantiomeric compounds of Kynurenine pathway, i.e. D, L-Kynurenine (KYN), in human serum and urine samples by cationic-β-CD and its synergistic dual chiral selector system
Olger Huaman et al.
Research in veterinary science, 124, 212-222 (2019-03-30)
Little information is currently available on therapeutic features of bovine mesenchymal stem cells (MSCs), despite the development of large animal experimental models including cattle may open alternative strategies for investigating MSC physiology and eventual applications for regenerative therapy. The aim
Exibir todos os documentos relacionados

Nossa equipe de cientistas tem experiência em todas as áreas de pesquisa, incluindo Life Sciences, ciência de materiais, síntese química, cromatografia, química analítica e muitas outras.

Entre em contato com a assistência técnica