F0301
Monoclonal Anti-CD56-FITC antibody produced in mouse
clone C5.9, purified immunoglobulin, buffered aqueous solution
Sinônimo(s):
Monoclonal Anti-CD56, Anti-NKH-1
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About This Item
Produtos recomendados
fonte biológica
mouse
Nível de qualidade
conjugado
FITC conjugate
forma do anticorpo
purified immunoglobulin
tipo de produto de anticorpo
primary antibodies
clone
C5.9, monoclonal
forma
buffered aqueous solution
peso molecular
antigen 150 kDa
reatividade de espécies
human
técnica(s)
flow cytometry: suitable
Isotipo
IgG2bκ
nº de adesão UniProt
Condições de expedição
wet ice
temperatura de armazenamento
2-8°C
modificação pós-traducional do alvo
unmodified
Informações sobre genes
human ... NCAM1(4684)
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Descrição geral
Prepared by conjugation of fluorescein isothiocyanate isomer 1 (FITC). This green dye is efficiently excited at 495 nm and emits at 525 nm.
Imunogênio
A cloned human NK cell line termed JT3
Aplicação
Monoclonal Anti-CD56-FITC antibody produced in mouse is suitable for fluorescence microscopy. It was also used for flow cytometric analysis.
Ações bioquímicas/fisiológicas
Neural Cell Adhesion Molecule (NCAM or the cluster of differentiation CD56) is a homophilic binding glycoprotein. It is expressed on the surface of neurons, glia, skeletal muscle and natural killer cells. CD56 can also be expressed in normal immature granulocytes at different expression levels in regenerative bone marrow. It is associated with cardiac genes induced by metabolic stress and its expression is associated with worsening hemodynamic parameters and major metabolic genes. CD56 is involved in left ventricular remodeling and can be implicated in heart failure. It is is developmentally regulated and may have an important role in cardiac development.
forma física
Solution in phosphate buffered saline, pH 7.4, containing 0.2% gelatin and 0.08% sodium azide.
Exoneração de responsabilidade
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Código de classe de armazenamento
10 - Combustible liquids
Classe de risco de água (WGK)
WGK 1
Ponto de fulgor (°F)
Not applicable
Ponto de fulgor (°C)
Not applicable
Certificados de análise (COA)
Busque Certificados de análise (COA) digitando o Número do Lote do produto. Os números de lote e remessa podem ser encontrados no rótulo de um produto após a palavra “Lot” ou “Batch”.
Já possui este produto?
Encontre a documentação dos produtos que você adquiriu recentemente na biblioteca de documentos.
A A Reyes et al.
Molecular and cellular biology, 11(3), 1654-1661 (1991-03-01)
The major membrane-associated or transmembrane isoforms of the neural cell adhesion molecule (NCAM) are generated by alternative splicing at the 3' end of the mRNA. Further diversity in NCAM structure is observed in the extracellular region of the polypeptide, where
Takaki Asano et al.
Frontiers in immunology, 9, 568-568 (2018-04-21)
Activated PI3Kδ syndrome (APDS) is a primary immunodeficiency characterized by recurrent respiratory tract infections, lymphoproliferation, and defective IgG production. Heterozygous mutations in PIK3CD, PIK3R1, or PTEN, which are related to the hyperactive phosphoinositide 3-kinase (PI3K) signaling, were recently presented to
Kazuo Muroi et al.
Journal of clinical and experimental hematopathology : JCEH, 53(3), 247-250 (2013-12-27)
Bone marrow mononuclear cells from 93 patients with hematological malignancies after allogeneic hematopoietic stem cell transplantation (AHSCT) were analyzed using flow cytometry (FCM). The disease was acute myeloblastic leukemia (50 patients), acute lymphoblastic leukemia, and others. Conditioning was myeloablative (80
E Oviedo-Orta et al.
Immunology, 99(4), 578-590 (2000-05-03)
The distribution and function of connexins (integral membrane proteins assembled into gap junction intercellular communication channels) were studied in human lymphocyte subpopulations. The expression of mRNA encoding connexins in peripheral blood and tonsil-derived T, B and natural killer (NK) lymphocytes
Branka Petricevic et al.
Journal of translational medicine, 11, 307-307 (2013-12-18)
Monoclonal antibodies (mAb), such as trastuzumab are a valuable addition to breast cancer therapy. Data obtained from neoadjuvant settings revealed that antibody-dependent cell-mediated cytotoxicity (ADCC) is a major mechanism of action for the mAb trastuzumab. Conflicting results still call into
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