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43407

Sigma-Aldrich

β-Dinucleotídeo de nicotinamida adenina

≥94% (HPLC), from yeast

Sinônimo(s):

β-DPN, β-NAD, Coenzima 1, Cozimase, DPN, NAD, Nadide, Nucleotídeo de difosfopiridina

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About This Item

Fórmula empírica (Notação de Hill):
C21H27N7O14P2 · xH2O
Número CAS:
53-84-9
Peso molecular:
663.43 (anhydrous basis)
Número CE:
200-184-4
Número MDL:
MFCD00036253
Código UNSPSC:
12352200
eCl@ss:
39200202
ID de substância PubChem:
24867168

fonte biológica

yeast

Ensaio

≥94% (HPLC)

Impurezas

≤10% water
≤4% solvent (methanol)

solubilidade

H2O: 0.1 g/mL, clear, faintly yellow
water: freely soluble

adequação

in accordance for determination of ADH

temperatura de armazenamento

−20°C

cadeia de caracteres SMILES

NC1=NC=NC2=C1N=CN2.O[C@@H]3[C@@H](COP(O)(OP(OC[C@@H](O4)[C@@H](O)[C@@H](O)[C@H]4[N+]5=CC=CC(C(N)=O)=C5)([O-])=O)=O)OC[C@@H]3O

InChI

1S/C21H27N7O14P2/c22-17-12-19(25-7-24-17)28(8-26-12)21-16(32)14(30)11(41-21)6-39-44(36,37)42-43(34,35)38-5-10-13(29)15(31)20(40-10)27-3-1-2-9(4-27)18(23)33/h1-4,7-8,10-11,13-16,20-21,29-32H,5-6H2,(H5-,22,23,24,25,33,34,35,36,37)/t10-,11-,13-,14-,15-,16-,20-,21-/m1/s1

chave InChI

BAWFJGJZGIEFAR-NNYOXOHSSA-N

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Aplicação

β-Nicotinamide adenine dinucleotide hydrate was used as a test compound for studying the structure and electrochemical properties of NADH electrocatalysts.

Ações bioquímicas/fisiológicas

β-Nicotinamide adenine dinucleotide is a cofactor for alcohol dehydrogenase that serves as an inhibitory neurotransmitter in visceral smooth muscle.
Aceptor de elétrons

Embalagem

Embalado com base no peso sólido.

Outras notas

Esta é a forma comum da NAD.

Código de classe de armazenamento

13 - Non Combustible Solids

Classe de risco de água (WGK)

WGK 3

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable

Equipamento de proteção individual

Eyeshields, Gloves, type N95 (US)

Certificados de análise (COA)

Busque Certificados de análise (COA) digitando o Número do Lote do produto. Os números de lote e remessa podem ser encontrados no rótulo de um produto após a palavra “Lot” ou “Batch”.

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Structure and Electrochemical Properties of Electrocatalysts for NADH Oxidation.
Rosalba A. Rincon
Electroanalysis, 22, 799-806 (2010)
Violeta N Mutafova-Yambolieva et al.
Proceedings of the National Academy of Sciences of the United States of America, 104(41), 16359-16364 (2007-10-05)
Peripheral inhibitory nerves are physiological regulators of the contractile behavior of visceral smooth muscles. One of the transmitters responsible for inhibitory neurotransmission has been reputed to be a purine, possibly ATP. However, the exact identity of this substance has never
Ana P Gomes et al.
Cell, 155(7), 1624-1638 (2013-12-24)
Ever since eukaryotes subsumed the bacterial ancestor of mitochondria, the nuclear and mitochondrial genomes have had to closely coordinate their activities, as each encode different subunits of the oxidative phosphorylation (OXPHOS) system. Mitochondrial dysfunction is a hallmark of aging, but
Christian Dölle et al.
The FEBS journal, 280(15), 3530-3541 (2013-04-27)
Mitochondrial metabolism is intimately connected to the universal coenzyme NAD. In addition to its role in redox reactions of energy transduction, NAD serves as substrate in regulatory reactions that lead to its degradation. Importantly, all types of the known NAD-consuming
Jeerus Sucharitakul et al.
The Journal of biological chemistry, 288(49), 35210-35221 (2013-10-17)
3-Hydroxybenzoate 6-hydroxylase (3HB6H) from Rhodococcus jostii RHA1 is an NADH-specific flavoprotein monooxygenase that catalyzes the para-hydroxylation of 3-hydroxybenzoate (3HB) to form 2,5-dihydroxybenzoate (2,5-DHB). Based on results from stopped-flow spectrophotometry, the reduced enzyme-3HB complex reacts with oxygen to form a C4a-peroxy
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