402RA-05A

Human Chondrocytes - Rheumatoid Arthritis: HC-RA, adult

• Código UNSPSC: 41106514
• NACRES: NA.81

Propriedades

• fonte biológica: human articular cartilage (rheumatoid arthritic)
• Nível de qualidade: 100
• embalagem: pkg of 500,000 cells
• fabricante/nome comercial: Cell Applications, Inc
• modo de crescimento: Adherent
• cariótipo: 2n = 46
• morfologia: chondrocyte
• técnica(s): cell culture | mammalian: suitable
• doença(s) relevante(s): arthritis
• Condições de expedição: dry ice
• temperatura de armazenamento: −196°C

Descrição

Descrição geral

Lot specific orders are not able to be placed through the web. Contact your local sales rep for more details.

HC-RA Human Chondrocytes are derived from human articular cartilage of donors with rheumatoid arthritis (RA). Rheumatoid arthritis is an inflammatory disease that is characterized by overproliferation of synovial cells and their infiltration into adjacent joint tissues, accompanied by gradual destruction of cartilage and bone erosion. Normally, chondrocytes are responsible for producing and maintaining the extracellular matrix of cartilage, but in RA cartilage, the environment is changed significantly due to inflammation and the invasion of other cells. Therefore, HC-RA can be a useful model to study the effects of those changes on chondrocyte biology. In parallel with normal HC, HC-RA can be used to investigate the differences between normal and pathological joints and evaluate potential treatment strategies.

Characterization: Positive for aggrecan after differentiation.

Origem de linhagem celular

Cartilage

Aplicação

model to study effects of RA on chondrocytes, investigate differences between normal and pathological joints and evaluate potential treatment strategies

Componentes

Basal Medium containing 10% FBS & 10% DMSO

Nota de preparo

• 1st passage, >500,000 cells in Basal Medium containing 10% FBS & 10% DMSO
• Can be cultured at least 10 doublings

Rotina de subcultura

Please refer to the HC-RA Culture Protocol.

Exoneração de responsabilidade

RESEARCH USE ONLY. This product is regulated in France when intended to be used for scientific purposes, including for import and export activities (Article L 1211-1 paragraph 2 of the Public Health Code). The purchaser (i.e. enduser) is required to obtain an import authorization from the France Ministry of Research referred in the Article L1245-5-1 II. of Public Health Code. By ordering this product, you are confirming that you have obtained the proper import authorization.

Informações de segurança

• Código de classe de armazenamento: 11 - Combustible Solids
• Classe de risco de água (WGK): WGK 3
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable