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Key Documents

227R-2

Sigma-Aldrich

BCL6 (EP278) Rabbit Monoclonal Primary Antibody

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About This Item

Código UNSPSC:
12352203
NACRES:
NA.41

fonte biológica

rabbit

Nível de qualidade

100
500

conjugado

unconjugated

forma do anticorpo

culture supernatant

tipo de produto de anticorpo

primary antibodies

clone

EP278, monoclonal

descrição

(For In Vitro Diagnostic Use in Select Regions (See Chart))

forma

buffered aqueous solution

reatividade de espécies

human

embalagem

bottle of 1.0 mL predilute (227R-27)
bottle of 7.0 mL predilute (227R-28)
vial of 0.1 mL concentrate (227R-24)
vial of 0.5 mL concentrate (227R-25)
vial of 1.0 mL concentrate (227R-26)
vial of 0.1 mL concentrate Research Use Only (227R-24-RUO)
vial of 1.0 mL concentrate Research Use Only (227R-26-RUO)
vial of 1.0 mL pre-dilute Research Use Only (227R-27-RUO)
vial of 7.0 mL pre-dilute ready-to-use Research Use Only (227R-28-RUO)

fabricante/nome comercial

Cell Marque

técnica(s)

immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:100-1:500

Isotipo

IgG

controle

tonsil

Condições de expedição

wet ice

temperatura de armazenamento

2-8°C

visualização

nuclear

Informações sobre genes

human ... BCL6(604)

Descrição geral

BCL6 is a transcriptional regulator gene which codes for a 706-amino-acid nuclear zinc finger protein.1 In normal tissue these antibodies have strong nuclear staining for a subset of B-lymphocytes, mostly located in germinal centers (GC).2 BCL6 antibodies stain malignant cells in follicular lymphoma,3 diffuse large B-cell lymphomas,4 Burkitt lymphoma,4 classical Hodgkin lymphoma,5 as well as majority of tumor cells in nodular lymphocyte predominant Hodgkin lymphoma.6 BCL6 expression has been also seen in anaplastic large cell lymphomas (ALCL).7

Qualidade


IVD

IVD

IVD

RUO

Ligação

BCL6 Positive Control Slides, Product No. 227S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).

forma física

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide.

Nota de preparo

Download the IFU specific to your product lot and formatNote: This requires a keycode which can be found on your packaging or product label.

Outras notas

For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com

Informações legais

Cell Marque is a trademark of Merck KGaA, Darmstadt, Germany

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Código de classe de armazenamento

12 - Non Combustible Liquids

Classe de risco de água (WGK)

WGK 2

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable


Certificados de análise (COA)

Busque Certificados de análise (COA) digitando o Número do Lote do produto. Os números de lote e remessa podem ser encontrados no rótulo de um produto após a palavra “Lot” ou “Batch”.

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Visite a Biblioteca de Documentos

Expression of BCL-6 protein and CD138/syndecan-1 as B-cell markers in Hodgkin's disease.
A Carbone et al.
The International journal of biological markers, 14(3), 144-148 (1999-11-24)
Maria Bai et al.
Leukemia & lymphoma, 47(3), 495-501 (2006-01-07)
The bcl6/CD10/MUM1/CD138 B-cell differentiation immunophenotypes were analysed in 101 cases of classical Hodgkin lymphomas (cHL) aiming to elucidate their histogenesis. Three major bcl6/CD10/MUM1/CD138 immunophenotypes were distinguished on the basis of the immunohistochemical positivity of Hodgkin and Reed-Sternberg (H/RS) cells: (a)
Arzu Saglam et al.
Tumori, 97(5), 634-638 (2011-12-14)
Several transcription factors predominantly used for B-cell lineage identification are also expressed in a small percentage of T cells within germinal centers and interfollicular areas. The aim of the study was to evaluate the expression of Mum-1, Oct-2 and Bcl-6
Antonino Carbone et al.
Human pathology, 41(5), 621-631 (2010-04-20)
Published in September 2008, the updated World Health Organization Classification of Tumors of Hematopoietic and Lymphoid Tissues introduces provisional borderline categories for lymphoma cases that demonstrate overlapping clinical, morphological, and/or immunophenotypic features between well-established entities. These overlapping features pose real
A Carbone et al.
Blood, 90(6), 2445-2450 (1997-10-06)
The expression pattern of the BCL-6 transcription factor has been assessed in normal and neoplastic B-cell populations and in Hodgkin's disease. However, little is known about BCL-6 expression and its biological significance in T-cell neoplasms. In this study, a series

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