S2002

Sodium azide

ReagentPlus^®, ≥99.5%

• Sinônimo(s): Hydrazoic acid sodium salt
• Fórmula linear: NaN₃
• Número CAS: 26628-22-8
• Peso molecular: 65.01
• Número CE: 247-852-1
• Número MDL: MFCD00003536
• Código UNSPSC: 12352201
• ID de substância PubChem: 24899504
• NACRES: NA.21

Propriedades

• fonte biológica: synthetic (inorganic)
• Nível de qualidade: 200
• linha de produto: ReagentPlus^®
• Ensaio: ≥99.5%
• forma: powder
• condição de armazenamento: (Tightly closed. Dry. Keep in a well-ventilated place. Do not store near acids.)
• técnica(s): cell based assay: suitable; immunohistochemistry: suitable
• cor: white
• pf: 370-425 °C
• solubilidade: soluble 65 g/L at 20 °C (completely)
• adequação: suitable for chromatography; suitable for derivatization
• aplicação(ões): sample preparation
• cadeia de caracteres SMILES: [Na]N=[N+]=[N-]
• InChI: 1S/N3.Na/c1-3-2;/q-1;+1
• chave InChI: PXIPVTKHYLBLMZ-UHFFFAOYSA-N

Descrição

Descrição geral

Sodium Azide (NaN3) is a potent inhibitor – a water-soluble crystalline powder that′s odorless. Widely recognized for its versatile applications, it plays a pivotal role across molecular biology, cell culture, and biochemical research. Sodium azide is commonly used as a bacteriostatic preservative in aqueous laboratory reagents and biological fluids. It is also a metabolic inhibitor, which inhibits oxidative phosphorylation. In cell culture, it maintains the integrity of your cell lines by preventing microbial contamination. Its application extends to molecular biology, where it aids in preserving nucleic acids for downstream analysis, ensuring the fidelity of your results.

Aplicação

Baylis-Hillman acetates such as ethyl 2-(acetoxyphenylmethyl)acrylate can undergo nucleophilic displacement by sodium azide in aqueous medium to form ethyl (E)-2-azidomethyl-3-phenylpropenoate.

Sodium azide is suitable for use in histopathology to prepare and store tissue samples. Also used as a component of staining buffer (HEPES buffer) for whole mount immunolabelling.
Catalyst for:

• Oxidative decarboxylation
• Michael addition reactions

Reagent for synthesis of

• Blue fluorescent copolymers
• Metal phosphonates
• Arenes via aminations

Ações bioquímicas/fisiológicas

Sodium azide is clinically used as a preservative in diluting fluid for counting red blood cells. It prevents capping and internalization of fluorescent surface-bound antibodies in various scientific applications, including flow cytometry.

Outras notas

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Informações legais

ReagentPlus is a registered trademark of Merck KGaA, Darmstadt, Germany

Informações de segurança

• Pictogramas: GHS06,GHS08,GHS09
• Palavra indicadora: Danger
• Frases de perigo: H300 + H310 + H330,H373,H410
• Declarações de precaução: P262 - P264 - P273 - P280 - P302 + P352 + P310 - P304 + P340 + P310
• Classificações de perigo: Acute Tox. 1 Dermal - Acute Tox. 2 Inhalation - Acute Tox. 2 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - STOT RE 2 Oral
• Órgãos-alvo: Brain
• Perigos de suplementos: EUH032
• Código de classe de armazenamento: 6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
• Classe de risco de água (WGK): WGK 2
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable