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51050

Sigma-Aldrich

Guanosine

≥98.0% (HPLC)

Sinônimo(s):

9-(β-D-Ribofuranosyl)guanine, Guanine-9-β-D-ribofuranoside

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About This Item

Fórmula empírica (Notação de Hill):
C10H13N5O5
Número CAS:
118-00-3
Peso molecular:
283.24
Beilstein:
625911
Número CE:
204-227-8
Número MDL:
MFCD00010182
Código UNSPSC:
41106305

Ensaio

≥98.0% (HPLC)

atividade óptica

[α]20/D −73±2°, c = 1.5% in 0.1 M NaOH

Impurezas

≤3% water

pf

250 °C (dec.) (lit.)

solubilidade

0.1 M NaOH: 0.1 g/mL, clear, slightly yellow

cadeia de caracteres SMILES

[H]O[H].NC1=Nc2c(ncn2[C@@H]3O[C@H](CO)[C@@H](O)[C@H]3O)C(=O)N1

InChI

1S/C10H13N5O5/c11-10-13-7-4(8(19)14-10)12-2-15(7)9-6(18)5(17)3(1-16)20-9/h2-3,5-6,9,16-18H,1H2,(H3,11,13,14,19)/t3-,5-,6-,9-/m1/s1

chave InChI

NYHBQMYGNKIUIF-UUOKFMHZSA-N

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Certificados de análise (COA)

Lot/Batch Number
1379265
1373414
1349587
1343816
1296319

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Ping Guo et al.
Journal of natural products, 74(7), 1575-1583 (2011-06-21)
Ten new neo-clerodane diterpenes, ajugaciliatins A-J (1-5, 8-12), along with 17 known analogues (6, 7, 13-27) were isolated from the whole plants of Ajuga ciliata Bunge. Their structures were elucidated by spectroscopic data analysis (IR, ESIMS, HRESIMS, 1D and 2D
Jing Xu et al.
Journal of natural products, 74(10), 2224-2230 (2011-09-21)
Ten myrsinol diterpenes, euphorbiaproliferins A-J (1-10), along with nine known analogues (11-19) were isolated from the roots of Euphorbia prolifera. Their structures were elucidated by spectroscopic data analysis (IR, ESIMS, HRESIMS, 1D and 2D NMR), and the structure of 1
Yanjie Sun et al.
Antimicrobial agents and chemotherapy, 51(1), 84-88 (2006-10-25)
Ribavirin (RBV) is a broad-spectrum antiviral agent that inhibits the production of infectious Hantaan virus (HTNV). Although the mechanism of action of RBV against HTNV is not understood, RBV is metabolized in human cells to both RBV-5'-monophosphate, which inhibits IMP
Craig H Steeves et al.
Bioorganic & medicinal chemistry letters, 21(18), 5188-5190 (2011-08-16)
CTP Synthase from Trypanosoma brucei (TbCTPS) catalyzes the conversion of UTP to CTP and is a recognized target for the development of antiprotozoal agents. GTP activates glutamine-dependent CTP formation catalyzed by TbCTPS at concentrations below 0.2 mM, but inhibits this
Zadkiel Alvarez et al.
Antimicrobial agents and chemotherapy, 54(12), 5329-5336 (2010-10-06)
Bacillus anthracis, the etiological agent of anthrax, has a dormant stage in its life cycle known as the endospore. When conditions become favorable, spores germinate and transform into vegetative bacteria. In inhalational anthrax, the most fatal manifestation of the disease

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