MABN372

Anti-CLN3 Antibody, Clone 2B8.2

clone 2B8.2, from mouse

• Sinônimo(s): Battenin, Batten disease protein, Protein CLN3
• Código UNSPSC: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

Propriedades

• fonte biológica: mouse
• Nível de qualidade: 100
• forma do anticorpo: purified immunoglobulin
• tipo de produto de anticorpo: primary antibodies
• clone: 2B8.2, monoclonal
• reatividade de espécies: mouse, human
• técnica(s): immunohistochemistry: suitable; western blot: suitable
• Isotipo: IgG1κ
• nº de adesão NCBI: NP_000077
• nº de adesão UniProt: Q13286
• Condições de expedição: wet ice
• modificação pós-traducional do alvo: unmodified
• Informações sobre genes: human ... CLN3(1201)

Descrição

Descrição geral

CLN3 protein is involved in lysosomal function. Mutations in this, as well as other neuronal ceroid-lipofuscinosis (CLN) genes, cause neurodegenerative diseases commonly known as Batten disease or collectively known as neuronal ceroid lipofuscinoses (NCLs).

Imunogênio

KLH-conjugated linear peptide corresponding to human CLN3.

Aplicação

Research Category
Neuroscience

Research Sub Category
Developmental Signaling

This Anti-CLN3 Antibody, Clone 2B8.2 is validated for use in Western Blotting and Immunohistochemistry for the detection of CLN3.

Western Blotting Analysis: 2.0 µg/mL from a representative lot detected CLN3 in 10 µg of A431 cell lysate.
Immunohistochemistry Analysis: A 1:50 dilution from a representative lot detected CLN3 in rat cerebellum and human thalamus tissue.

Qualidade

Evaluated by Western Blotting in HepG2 cell lysate.

Western Blotting Analysis: 2.0 µg/mL of this antibody detected CLN3 in 10 µg of HepG2 cell lysate.

Descrição-alvo

~45 kDa observed. Uniprot describes 5 isoforms produced by alternative splicing at ~45, ~42, ~37, ~35, and ~28 kDa

forma física

Format: Purified

Protein G Purified

Purified mouse monoclonal IgG1κ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

Armazenamento e estabilidade

Stable for 1 year at 2-8°C from date of receipt.

Outras notas

Concentration: Please refer to lot specific datasheet.

Exoneração de responsabilidade

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Informações de segurança

• Código de classe de armazenamento: 12 - Non Combustible Liquids
• Classe de risco de água (WGK): WGK 1
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable