AB9210
Anti-Insulin Degrading Enzyme Antibody
serum, Chemicon®
Sinônimo(s):
IDE, Insulysin, Insulinase
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About This Item
Código UNSPSC:
12352203
eCl@ss:
32160702
NACRES:
NA.41
Produtos recomendados
fonte biológica
rabbit
Nível de qualidade
forma do anticorpo
serum
tipo de produto de anticorpo
primary antibodies
clone
polyclonal
reatividade de espécies
rat
embalagem
antibody small pack of 25 μL
fabricante/nome comercial
Chemicon®
técnica(s)
western blot: suitable
nº de adesão NCBI
nº de adesão UniProt
Condições de expedição
dry ice
temperatura de armazenamento
−20°C
modificação pós-traducional do alvo
unmodified
Informações sobre genes
rat ... Ins1(24505)
Especificidade
Insulin Degrading Enzyme (IDE). It is expected that the antibody will also react with human and mouse due to immunogen sequence homology.
Imunogênio
Synthetic peptide from rat IDE.
Aplicação
Anti-Insulin Degrading Enzyme Antibody is an antibody against Insulin Degrading Enzyme for use in WB.
Research Category
Neuroscience
Neuroscience
Research Sub Category
Neurodegenerative Diseases
Neurodegenerative Diseases
Western blotting: 1:10,000-1:20,000. The antibody recognizes a protein of ~110 kDa on rat liver tissue lysate.
Optimal working dilutions must be determined by the end user.
Optimal working dilutions must be determined by the end user.
Qualidade
Tested
forma física
Rabbit serum. Liquid.
Armazenamento e estabilidade
Maintain at -20°C in undiluted aliquots for up to 6 months after date of receipt. Avoid repeated freeze/thaw cycles.
Outras notas
Please refer to lot specific datasheet.
Informações legais
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
Exoneração de responsabilidade
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Código de classe de armazenamento
10 - Combustible liquids
Classe de risco de água (WGK)
WGK 1
Ponto de fulgor (°F)
Not applicable
Ponto de fulgor (°C)
Not applicable
Certificados de análise (COA)
Busque Certificados de análise (COA) digitando o Número do Lote do produto. Os números de lote e remessa podem ser encontrados no rótulo de um produto após a palavra “Lot” ou “Batch”.
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Carlos M González-Casimiro et al.
Cells, 10(9) (2021-09-29)
Insulin-degrading enzyme (IDE) is a highly conserved and ubiquitously expressed Zn2+-metallopeptidase that regulates hepatic insulin sensitivity, albeit its regulation in response to the fasting-to-postprandial transition is poorly understood. In this work, we studied the regulation of IDE mRNA and protein
Beatriz Merino et al.
Metabolism: clinical and experimental, 113, 154352-154352 (2020-09-12)
The insulin-degrading enzyme (IDE) is a metalloendopeptidase with a high affinity for insulin. Human genetic polymorphisms in Ide have been linked to increased risk for T2DM. In mice, hepatic Ide ablation causes glucose intolerance and insulin resistance when mice are
Miriam Corraliza-Gómez et al.
Cells, 11(2) (2022-01-22)
The insulin-degrading enzyme (IDE) is a zinc-dependent metalloendopeptidase that belongs to the M16A metalloprotease family. IDE is markedly expressed in the brain, where it is particularly relevant due to its in vitro amyloid beta (Aβ)-degrading activity. The subcellular localization of
Jéssica Taday et al.
Metabolites, 14(3) (2024-03-27)
Astrocytes play fundamental roles in the maintenance of brain homeostasis. The dysfunction of these cells is widely associated with brain disorders, which are often characterized by variations in the astrocyte protein markers GFAP and S100B, in addition to alterations in
Enrique Jurado-Ruiz et al.
Scientific reports, 9(1), 11311-11311 (2019-08-07)
Dietary composition plays an important role in the pathophysiology of type 2 diabetes. Monounsaturated fatty acid consumption has been positively associated with improved insulin sensitivity and β-cell function. We examined whether an extra virgin olive oil (EVOO) high fat diet
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