8.22336

Thioglycolic acid

for synthesis

• Sinônimo(s): Thioglycolic acid, Mercaptoacetic acid, 2-Mercaptoethanoic acid
• Fórmula empírica (Notação de Hill): C₂H₄O₂S
• Número CAS: 68-11-1
• Peso molecular: 92.12
• Número MDL: MFCD00004876
• Código UNSPSC: 12352106
• Número do índice EC: 200-677-4
• NACRES: NA.22

Propriedades

• pressão de vapor: 0.1 hPa ( 20 °C)
• Nível de qualidade: 200
• forma: liquid
• potência: 73 mg/kg LD₅₀, oral (Rat)
• pH: 1 (20 °C in H₂O)
• pb: 220 °C/1013 hPa (decomposition)
• pf: -16.5 °C
• temperatura de transição: flash point 131.5 °C
• densidade: 1.325 g/cm³ at 20 °C
• temperatura de armazenamento: 2-8°C
• InChI: 1S/C2H4O2S/c3-2(4)1-5/h5H,1H2,(H,3,4)
• chave InChI: CWERGRDVMFNCDR-UHFFFAOYSA-N

Descrição

Aplicação

• Biocompatible Drug Delivery Films: Thioglycolic acid enhances the film-forming ability and bioadhesiveness of mucilaginous polysaccharides derived from Cassia uniflora seeds. This innovation is pivotal in drug delivery applications, offering controlled release and improved mucosal adhesion properties (Deore et al., 2024).
• Surface Plasmon Resonance in Nanoparticle Research: The interfacial reactivity of gold nanoparticles can be inferred via surface plasmon resonance measurements, with thioglycolic acid playing a crucial role in modifying nanoparticle surfaces to enhance their reactive properties. This is significant for advancements in nanotechnology and material sciences (Romain et al., 2023).
• Enhanced SERS for Virus Detection: Thioglycolic acid contributes to the fabrication of flexible electrospinning nano-fiber membranes that are pivotal in the detection of respiratory tract transmission viruses using Surface Enhanced Raman Scattering (SERS). This application is crucial in improving public health surveillance and response systems (Sun et al., 2024).

Nota de análise

Assay (iodometric): ≥ 95.0 %
Density (d 20 °C/ 4 °C): 1.325 - 1.335
Identity (IR): passes test
The assay stated on the certificate of analysis refers to the date of examination. A gradual substance-specific content reduction, especially at higher temperatures, must be expected. The average content reduction at the required storage temperature of +2°c to +8°C is about 1% per month.

Informações de segurança

• Pictogramas: GHS05,GHS06
• Palavra indicadora: Danger
• Frases de perigo: H301 + H311 + H331 - H314 - H317
• Declarações de precaução: P261 - P270 - P280 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338
• Classificações de perigo: Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Eye Dam. 1 - Skin Corr. 1B - Skin Sens. 1B
• Código de classe de armazenamento: 6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• Classe de risco de água (WGK): WGK 1
• Ponto de fulgor (°F): 266.0 °F - closed cup
• Ponto de fulgor (°C): 130 °C - closed cup