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Sigma-Aldrich

MAP Kinase 2/Erk2 Protein, inactive, Mouse, 50 g

Unactive, recombinant full-length mouse p42 MAP Kinase 2/Erk2 fused with GST at the N terminus, for use in Kinase Assays.

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About This Item

Código UNSPSC:
12352202
eCl@ss:
32160405
NACRES:
NA.41

fonte biológica

mouse

Nível de qualidade

recombinante

expressed in E. coli

peso molecular

Mw 67.8 kDa

fabricante/nome comercial

Upstate®

técnica(s)

activity assay: suitable (kinase)

nº de adesão NCBI

nº de adesão UniProt

Condições de expedição

dry ice

Descrição geral

Product Source: expressed in E coli
Recombinant full-length mouse p42 MAP Kinase 2/Erk2 fused with GST at the N terminus

Qualidade

routinely evaluated by phosphorylation of MBP (Catalog # 13-104) substrate in vitro.

Outras notas

For Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme.

Informações legais

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

Pictogramas

Exclamation mark

Palavra indicadora

Warning

Frases de perigo

Classificações de perigo

Skin Sens. 1

Código de classe de armazenamento

10 - Combustible liquids

Classe de risco de água (WGK)

WGK 2


Certificados de análise (COA)

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Tian-Rui Xu et al.
The Biochemical journal, 413(1), 51-60 (2008-04-26)
FRET (fluorescence resonance energy transfer) and co-immunoprecipitation studies confirmed the capacity of beta-arrestin 2 to self-associate. Amino acids potentially involved in direct protein-protein interaction were identified via combinations of spot-immobilized peptide arrays and mapping of surface exposure. Among potential key
Maofu Fu et al.
Methods in molecular biology (Clifton, N.J.), 284, 15-36 (2004-06-03)
Signal transduction pathways mediate cell-cell interactions and integrate signals from the extracellular environment through specific receptors at the cell membrane. They play a pivotal role in regulating cellular growth and differentiation and in mediating many physiological and pathological processes, such
D Aronson et al.
The Journal of biological chemistry, 272(41), 25636-25640 (1997-11-05)
Contractile activity plays a critical role in the regulation of gene transcription in skeletal muscle, which in turn determines muscle functional capabilities. However, little is known about the molecular signaling mechanisms that convert contractile activity into gene regulatory responses in
O Zugasti et al.
Molecular and cellular biology, 21(19), 6706-6717 (2001-09-05)
Signals from the extracellular matrix are essential for the survival of many cell types. Dominant-negative mutants of two members of Rho family GTPases, Rac1 and Cdc42, mimic the loss of anchorage in primary mouse fibroblasts and are potent inducers of
Shawna D Persaud et al.
Cellular signalling, 25(1), 19-25 (2012-09-18)
All-trans retinoic acid (atRA), one of the active ingredients of vitamin A, exerts canonical activities to regulate gene expression mediated by nuclear RA receptors (RARs). AtRA could also elicit certain non-canonical activities including, mostly, rapid activation of extracellular signal regulated

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