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T-037

Supelco

Testosterone solution

1.0 mg/mL in acetonitrile, ampule of 1 mL, certified reference material, Cerilliant®

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About This Item

Fórmula empírica (Notação de Hill):
C19H28O2
Número CAS:
58-22-0
Peso molecular:
288.42
Número MDL:
MFCD00003654
Código UNSPSC:
41116107
ID de substância PubChem:
329826604
NACRES:
NA.24

grau

certified reference material

forma

liquid

Características

Snap-N-Spike®/Snap-N-Shoot®

embalagem

ampule of 1 mL

fabricante/nome comercial

Cerilliant®

concentração

1.0 mg/mL in acetonitrile

técnica(s)

gas chromatography (GC): suitable
liquid chromatography (LC): suitable

aplicação(ões)

clinical testing

formato

single component solution

temperatura de armazenamento

−20°C

cadeia de caracteres SMILES

CC12CCC3C(CCC4=CC(=O)CCC34C)C1CCC2O

InChI

1S/C19H28O2/c1-18-9-7-13(20)11-12(18)3-4-14-15-5-6-17(21)19(15,2)10-8-16(14)18/h11,14-17,21H,3-10H2,1-2H3/t14-,15-,16-,17-,18-,19-/m0/s1

chave InChI

MUMGGOZAMZWBJJ-DYKIIFRCSA-N

Informações sobre genes

human ... AR(367)

Descrição geral

A certified solution standard applicable to use in sports testing, urine drug testing, and diagnostic testing by LC-MS/MS or GC/MS. Testosterone, a hormone from the androgen group, is an important sex hormone and anabolic steroid often abused in sports.

Aplicação


  • Chemical Castration Studies: Testosterone solution is employed in veterinary applications, notably in the chemical castration of dogs using calcium chloride, demonstrating its utility in reproductive health management and animal welfare (Nader et al., 2023).

  • Neuroendocrine Research: It is utilized in studying the interplay between hypothalamic subunits and sex hormone levels in Alzheimer′s disease, highlighting its critical role in understanding neurodegenerative diseases and the neuroendocrine system (Ofori et al., 2024).

  • Endocrine Research: Testosterone solution is vital for research into the effects of melatonin on reproductive functions in hypothyroidism models, aiding in the exploration of hormonal interactions and therapeutic targets (Ezzat et al., 2024).

  • Reproductive Biology: In animal studies, testosterone is crucial for assessing the impact of treatments like intratesticular injections on sperm quality, oxidative stress, and testicular pathology, providing insights into male fertility and potential treatments (Baqerkhani et al., 2024).

  • Pharmacodynamics in Dermatology: The hormone′s solutions are used in pharmacodynamic studies to assess treatments for conditions like androgenetic alopecia, showcasing its importance in dermatological and biochemical research (Li et al., 2024).

Informações legais

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

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Pictogramas

FlameExclamation mark
GHS02,GHS07

Palavra indicadora

Danger

Classificações de perigo

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Flam. Liq. 2

Código de classe de armazenamento

3 - Flammable liquids

Classe de risco de água (WGK)

WGK 2

Ponto de fulgor (°F)

35.6 °F - closed cup

Ponto de fulgor (°C)

2 °C - closed cup

Certificados de análise (COA)

Busque Certificados de análise (COA) digitando o Número do Lote do produto. Os números de lote e remessa podem ser encontrados no rótulo de um produto após a palavra “Lot” ou “Batch”.

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David J Handelsman
The Journal of clinical endocrinology and metabolism, 91(5), 1646-1653 (2006-02-16)
The objective of the study was to review the rationale underlying the banning of human chorionic gonadotropin (hCG) and estrogen blockers (antiestrogens, specific estrogen receptor modulators, aromatase inhibitors) in sports for male and female athletes in the light of gender
Y Zimmerman et al.
Human reproduction update, 20(1), 76-105 (2013-10-02)
BACKGROUND; Combined oral contraceptives (COCs) reduce levels of androgen, especially testosterone (T), by inhibiting ovarian and adrenal androgen synthesis and by increasing levels of sex hormone-binding globulin (SHBG). Although this suppressive effect has been investigated by numerous studies over many
Frances S Chen et al.
Social cognitive and affective neuroscience, 10(6), 797-800 (2014-09-07)
Physical size and strength are associated with dominance and threat. The current study tested (i) whether men's evaluations of male strangers would be negatively influenced by cues indicating physical formidability, and (ii) whether these evaluations would be influenced by oxytocin
Andrea C Lo et al.
International journal of radiation oncology, biology, physics, 88(1), 87-93 (2013-12-18)
To determine (1) the prognostic utility of prostate-specific antigen (PSA) concentration at 45 to 60 months (48mPSA) after low-dose-rate prostate brachytherapy (LDR-PB); (2) the predictors of 48mPSA; and (3) the prognostic utility of directional trends between PSA levels at 24
James R Bell et al.
American journal of physiology. Heart and circulatory physiology, 306(9), H1265-H1274 (2014-03-13)
Estrogen in females is conventionally considered a cardioprotective influence, but a role for estrogen in male cardioprotection has yet to be defined. Estrogen biosynthesis from testosterone is regulated by aromatase. Aromatase has recently been shown to be expressed in the
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