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Sigma-Aldrich

Isoflurane

Sinônimo(s):

Isoflurane, 1-Chloro-1-(difluoromethoxy)-2,2,2-trifluoroethane, 1-Chloro-2,2,2-trifluoroethyl difluoromethyl ether

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About This Item

Fórmula empírica (Notação de Hill):
C3H2ClF5O
Número CAS:
26675-46-7
Peso molecular:
184.49
Número CE:
247-897-7
Número MDL:
MFCD00066609
Código UNSPSC:
12352100
ID de substância PubChem:
329768352
NACRES:
NA.22

pressão de vapor

238 mmHg ( 20 °C)

forma

liquid

índice de refração

n20/D 1.302

pb

48.5 °C

densidade

1.510 g/mL at 25 °C

temperatura de armazenamento

2-8°C

cadeia de caracteres SMILES

FC(F)OC(Cl)C(F)(F)F

InChI

1S/C3H2ClF5O/c4-1(3(7,8)9)10-2(5)6/h1-2H

chave InChI

PIWKPBJCKXDKJR-UHFFFAOYSA-N

Informações sobre genes

human ... GABRA1(2554) , GABRA2(2555) , GABRA3(2556) , GABRA4(2557) , GABRA5(2558) , GABRA6(2559) , GABRB1(2560) , GABRB2(2561) , GABRB3(2562) , GABRD(2563) , GABRE(2564) , GABRG1(2565) , GABRG2(2566) , GABRG3(2567) , GABRP(2568) , GABRQ(55879) , GLRA1(2741) , GLRB(2743) , KCNK10(54207) , KCNK18(338567) , KCNK2(3776) , KCNK3(3777) , KCNK9(51305)

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Descrição geral

Isofluraneis a fluorinated methyl ether and isomer of enflurane. The Federal DrugAdministration (FDA) has approved it for use as a volatile anesthetic to induceand maintain general anesthesia.

Aplicação

Isoflurane is a volatile anesthetic agent mainly used to study its interaction with the biological system.

Pictogramas

Exclamation mark
GHS07

Palavra indicadora

Warning

Frases de perigo

H336

Classificações de perigo

STOT SE 3

Órgãos-alvo

Central nervous system

Código de classe de armazenamento

10 - Combustible liquids

Classe de risco de água (WGK)

WGK 3

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable

Certificados de análise (COA)

Busque Certificados de análise (COA) digitando o Número do Lote do produto. Os números de lote e remessa podem ser encontrados no rótulo de um produto após a palavra “Lot” ou “Batch”.

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Satya Prathyusha Bhamidimarri et al.
Structure (London, England : 1993), 27(2), 268-280 (2018-12-18)
Research efforts to discover potential new antibiotics for Gram-negative bacteria suffer from high attrition rates due to the synergistic action of efflux systems and the limited permeability of the outer membrane (OM). One strategy to overcome the OM permeability barrier
Isoflurane-induced neuroapoptosis in the neonatal rhesus macaque brain.
Brambrink AM, et al.
Anesthesiology, 112(4), 834-841 (2010)
Wenjuan Sun et al.
Frontiers in pharmacology, 12, 708575-708575 (2021-10-01)
Maslinic acid (MA), also named crategolic acid, is a pentacyclic triterpene extracted from fruits and vegetables. Although various beneficial pharmacological effects of MA have been revealed, its effect on renal fibrosis remains unclear. This study was designed to clarify whether
Hao Zhang et al.
Molecular medicine reports, 22(2), 915-925 (2020-07-07)
Dilated cardiomyopathy (DCM) is a primary cardiomyopathy with high mortality. The aim of the present study was to identify the related genes in DCM. The four expression profiles (GSE17800, GSE21610, GSE42955 and GSE79962) downloaded from the Gene Expression Omnibus (GEO)
Sherrefa R Burchell et al.
Journal of investigative medicine : the official publication of the American Federation for Clinical Research, 61(7), 1078-1083 (2013-07-26)
Isoflurane is a volatile anesthetic that is widely used clinically as an inhalational anesthetic. In recent years, several studies have indicated that isoflurane has neuroprotective properties. This has led to the beneficial effects of isoflurane being analyzed in both cell
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