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Merck

WT1

Wilms tumor 1

Sinônimos:
AWT1, EWS-WT1, GUD, NPHS4, WAGR, WIT-2, WT33
Espécies:
ID UniProtKB:
ID do gene:
  • Human(7490) Summary: This gene encodes a transcription factor that contains four zinc-finger motifs at the C-terminus and a proline/glutamine-rich DNA-binding domain at the N-terminus. It has an essential role in the normal development of the urogenital system, and it is mutated in a small subset of patients with Wilm's tumors. This gene exhibits complex tissue-specific and polymorphic imprinting pattern, with biallelic, and monoallelic expression from the maternal and paternal alleles in different tissues. Multiple transcript variants have been described. In several variants, there is evidence for the use of a non-AUG (CUG) translation initiation site upstream of and in-frame with the first AUG. Authors of PMID:7926762 also provide evidence that WT1 mRNA undergoes RNA editing in human and rat, and that this process is tissue-restricted and developmentally regulated. [provided by RefSeq, Oct 2010]
  • Mouse(22431) Wilms tumor 1 homolog
  • Rat(24883) Wilms tumor 1
  • domestic guinea pig(100716139) Wilms tumor 1
  • dog(609253) Wilms tumor 1
  • sheep(100101227) Wilms tumor 1
  • naked mole-rat(101714640) Wilms tumor 1
  • cow(280959) Wilms tumor 1
  • chicken(396139) Wilms tumor 1
  • cow(782183) Wilms tumor 1
  • cow(614584) Wilms tumor 1
  • domestic cat(101088518) Wilms tumor 1

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Antibodies

Número do produto
Descrição
Reatividade de espécies
Aplicação
Anti-Wilms′ Tumor Antibody, NT, clone 6F-H2, clone 6F-H2, Chemicon®, from mouse,
Reatividade de espécies
human, mouse
Aplicação
immunocytochemistry
immunofluorescence

immunohistochemistry

immunoprecipitation (IP)

western blot
Anti-WT1 Antibody, clone 6F-H2, clone 6F-H2, Upstate®, from mouse,
Reatividade de espécies
human
Aplicação
immunocytochemistry
immunohistochemistry

western blot
Anti-Wilms′ Tumor Antibody, NT clone 6F-H2, Ascites Free, clone 6F-H2, from mouse,
Reatividade de espécies
human, mouse
Aplicação
immunocytochemistry
immunofluorescence

immunohistochemistry

immunoprecipitation (IP)

western blot
Anti-WT1, affinity isolated antibody,
Reatividade de espécies
dog, human, mouse, rabbit, rat
Aplicação
immunohistochemistry
western blot
Anti-WT1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Reatividade de espécies
human
Aplicação
immunofluorescence

Proteins

Número do produto
Descrição
Espécies
WT-1 (+KTS) human, recombinant, expressed in insect cells, ≥60% (SDS-PAGE),
Espécies
human
WT-1 (-KTS) human, recombinant, expressed in insect cells, ≥60% (SDS-PAGE),
Espécies
human

esiRNA

Número do produto
Descrição
Espécies
MISSION® esiRNA, targeting human WT1,
Espécies
human