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Merck

SRF

serum response factor (c-fos serum response element-binding transcription factor)

Sinônimos:
MCM1
Espécies:
ID UniProtKB:
ID do gene:
  • Human(6722) Summary: This gene encodes a ubiquitous nuclear protein that stimulates both cell proliferation and differentiation. It is a member of the MADS (MCM1, Agamous, Deficiens, and SRF) box superfamily of transcription factors. This protein binds to the serum response element (SRE) in the promoter region of target genes. This protein regulates the activity of many immediate-early genes, for example c-fos, and thereby participates in cell cycle regulation, apoptosis, cell growth, and cell differentiation. This gene is the downstream target of many pathways; for example, the mitogen-activated protein kinase pathway (MAPK) that acts through the ternary complex factors (TCFs). [provided by RefSeq, Jul 2008]
  • Mouse(20807) serum response factor
  • Rat(501099) serum response factor (c-fos serum response element-binding transcription factor)
  • fruit fly(252723) Surf wings
  • chicken(396103) serum response factor (c-fos serum response element-binding transcription factor)
  • domestic cat(101085210) serum response factor (c-fos serum response element-binding transcription factor)
  • dog(612861) serum response factor (c-fos serum response element-binding transcription factor)
  • cow(533039) serum response factor (c-fos serum response element-binding transcription factor)
  • sheep(101111402) serum response factor (c-fos serum response element-binding transcription factor)
  • domestic guinea pig(100715998) serum response factor (c-fos serum response element-binding transcription factor)
  • naked mole-rat(101719000) serum response factor (c-fos serum response element-binding transcription factor)

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Antibodies

Número do produto
Descrição
Reatividade de espécies
Aplicação
Anti-SRF Antibody, clone 1H14 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Reatividade de espécies
human, mouse, rat
Aplicação
immunocytochemistry
immunohistochemistry

western blot
Anti-SRF antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reatividade de espécies
human
Aplicação
immunohistochemistry
western blot
Anti-SRF antibody produced in rabbit, affinity isolated antibody,
Reatividade de espécies
human, mouse, rat
Aplicação
ELISA
immunohistochemistry

western blot
Anti-SRF antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
Reatividade de espécies
bovine, canine, human, mouse
Aplicação
ELISA
western blot
Anti-phospho-SRF (pSer99) antibody produced in rabbit, affinity isolated antibody,
Reatividade de espécies
human, mouse, rat
Aplicação
ELISA
immunohistochemistry

western blot

Proteins

Número do produto
Descrição
Espécies
C-fos, proto oncogene human, recombinant, expressed in insect cells, ≥70% (SDS-PAGE),
Espécies
human

esiRNA

Número do produto
Descrição
Espécies
MISSION® esiRNA, targeting human SRF,
Espécies
human