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Merck

SRC

v-src avian sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog

Sinônimos:
ASV, SRC1, c-SRC, p60-Src
Espécies:
Human SRC (6714), Mouse Src (20779), Rat Src (83805), Zebrafish src (325084), chicken SRC (396442), domestic cat SRC (101100378), dog SRC (485864), sheep SRC (101103084), cow SRC (535742), domestic guinea pig Src (100728509)
ID UniProtKB:
P12931, E1P5V4, Q76P87, Q86VB9, Q9H5A8
ID do gene:
  • Human(6714) Summary: This gene is highly similar to the v-src gene of Rous sarcoma virus. This proto-oncogene may play a role in the regulation of embryonic development and cell growth. The protein encoded by this gene is a tyrosine-protein kinase whose activity can be inhibited by phosphorylation by c-SRC kinase. Mutations in this gene could be involved in the malignant progression of colon cancer. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]
  • Mouse(20779) Rous sarcoma oncogene
  • Rat(83805) v-src avian sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog
  • Zebrafish(325084) v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)
  • chicken(396442) v-src sarcoma viral oncogene
  • domestic cat(101100378) v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)
  • dog(485864) v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)
  • sheep(101103084) v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)
  • cow(535742) v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)
  • domestic guinea pig(100728509) Rous sarcoma oncogene
  • naked mole-rat(101703827) v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)

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Small Molecule - Antagonist

Número do produto
Descrição
Espécies
695017
Ácido fosfórico, ACS reagent, ≥85 wt. % in H2O,
Espécies
human
345245
Ácido fosfórico, 85 wt. % in H2O, 99.99% trace metals basis,
Espécies
human
438081
Ácido fosfórico, ACS reagent, ≥85 wt. % in H2O,
Espécies
human
27109
Ácido cítrico, meets analytical specification of Ph. Eur., BP, USP, E330, anhydrous, 99.5-100.5% (based on anhydrous substance),
Espécies
human
30417
Ácido fosfórico, puriss. p.a., ACS reagent, reag. ISO, reag. Ph. Eur., ≥85%,
Espécies
human

Antibodies

Número do produto
Descrição
Reatividade de espécies
Aplicação
05-677
Anti-phospho-Src (Tyr416) Antibody, clone 9A6, clone 9A6, Upstate®, from mouse,
Reatividade de espécies
human, mouse
Aplicação
immunoprecipitation (IP)
western blot
07-909
Anti-phospho-Src (Tyr418) Antibody, Upstate®, from rabbit,
Reatividade de espécies
chicken, human, mouse
Aplicação
immunocytochemistry
immunohistochemistry
western blot
HPA030875
Anti-SRC antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reatividade de espécies
human
Aplicação
immunofluorescence
western blot
04-772
Anti-Src Antibody, CT, clone NL19 | 04-772, clone NL19, Upstate®, from rabbit,
Reatividade de espécies
human, mouse, rat
Aplicação
immunoprecipitation (IP)
western blot
SAB5300367
Monoclonal Anti-SRC antibody produced in mouse, clone 1F11, ascites fluid,
Reatividade de espécies
human
Aplicação
ELISA
flow cytometry
immunohistochemistry
western blot

Small Molecule - Inhibitor

Número do produto
Descrição
Espécies
S9692
SU 6656, ≥98% (HPLC),
Espécies
human
R2146
Radicicol from Diheterospora chlamydosporia, solid,
Espécies
human, rat
PZ0192
Bosutinib, ≥98% (HPLC),
Espécies
human
E2250
Ellagic acid, ≥95% (HPLC), powder, from tree bark,
Espécies
human, rat
T182
Tyrphostin A9, solid,
Espécies
mouse, human

Kits

Número do produto
Descrição
Espécies
20-121
Src Kinase Reaction Buffer, ,
Espécies
human

Proteins

Número do produto
Descrição
Espécies
14-326-M
Src Protein, active, 10 µg, Active, N-Terminal His6-tagged, recombinant, full-length, human Src. For use in Kinase Assays.,
Espécies
human
S1076
SRC, active, GST tagged human, PRECISIO® Kinase, recombinant, expressed in E. coli, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Espécies
human
S5564
SRC N1 human, ≥60% (SDS-PAGE), recombinant, expressed in baculovirus infected insect cells, buffered aqueous glycerol solution,
Espécies
human
14-748-M
Src (T341M) Protein, active, 10 µg, Active, N-terminal 6His-tagged, recombinant, full-length human Src, containing the T341M mutation. For use in Kinase Assays.,
Espécies
human
14-746-M
Src (1-530) Protein, active, 10 µg, ,
Espécies
human

esiRNA

Número do produto
Descrição
Espécies
EMU071351
MISSION® esiRNA, targeting mouse Src,
Espécies
mouse

Small Molecule - Substrate

Número do produto
Descrição
Espécies
12-140
Src Substrate Peptide, Src Substrate Peptide primarily used in Kinase Assays.,
Espécies
human