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Merck

PRPH2

peripherin 2 (retinal degeneration, slow)

Sinônimos:
AOFMD, AVMD, CACD2, DS, PRPH, RDS, RP7, TSPAN22, rd2
Espécies:
ID UniProtKB:
ID do gene:
  • Human(5961) Summary: The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein found in the outer segment of both rod and cone photoreceptor cells. It may function as an adhesion molecule involved in stabilization and compaction of outer segment disks or in the maintenance of the curvature of the rim. This protein is essential for disk morphogenesis. Defects in this gene are associated with both central and peripheral retinal degenerations. Some of the various phenotypically different disorders are autosomal dominant retinitis pigmentosa, progressive macular degeneration, macular dystrophy and retinitis pigmentosa digenic. [provided by RefSeq, Jul 2008]
  • Mouse(19133) peripherin 2
  • Rat(25534) peripherin 2
  • domestic cat(727697) peripherin 2 (retinal degeneration, slow)
  • sheep(101109569) peripherin 2 (retinal degeneration, slow)
  • cow(280907) peripherin 2 (retinal degeneration, slow)
  • chicken(395899) peripherin 2 (retinal degeneration, slow)
  • naked mole-rat(101702401) peripherin 2 (retinal degeneration, slow)
  • dog(403972) peripherin 2 (retinal degeneration, slow)
  • domestic guinea pig(100713395) peripherin 2 (retinal degeneration, slow)

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Antibodies

Número do produto
Descrição
Reatividade de espécies
Aplicação
Anticorpo antiperiferina, serum, Chemicon®,
Reatividade de espécies
bovine, human, mouse, pig, rat
Aplicação
immunohistochemistry
western blot
Anti-Peripherin Antibody, clone 8G2, culture supernatant, clone 8G2, Chemicon®,
Reatividade de espécies
bovine, human, mouse, pig, rat
Aplicação
immunocytochemistry
immunohistochemistry

western blot
Anti-Peripherin-2 Antibody, clone 6B10.1, clone 6B10.1, from mouse,
Reatividade de espécies
human, mouse, rat
Aplicação
immunohistochemistry
western blot
Anti-PRPH2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reatividade de espécies
human
Aplicação
immunohistochemistry
western blot
Anti-Peripherin-2 Antibody, clone 5H2, clone 5H2, from mouse,
Reatividade de espécies
bovine, mouse
Aplicação
immunofluorescence
radioimmunoassay

western blot

esiRNA

Número do produto
Descrição
Espécies
MISSION® esiRNA, targeting human PRPH2,
Espécies
human