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Merck

MMP2

matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)

Sinônimos:
CLG4, CLG4A, MMP-II, MONA, TBE-1
Espécies:
ID UniProtKB:
ID do gene:
  • Human(4313) Summary: Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. This gene encodes an enzyme which degrades type IV collagen, the major structural component of basement membranes. The enzyme plays a role in endometrial menstrual breakdown, regulation of vascularization and the inflammatory response. Mutations in this gene have been associated with Winchester syndrome and Nodulosis-Arthropathy-Osteolysis (NAO) syndrome. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
  • Mouse(17390) matrix metallopeptidase 2
  • Rat(81686) matrix metallopeptidase 2
  • naked mole-rat(101696977) matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)
  • cow(282872) matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)
  • sheep(443115) matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)
  • chicken(386583) matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)
  • domestic guinea pig(100719361) matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)
  • dog(403733) matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)
  • Zebrafish(337179) matrix metalloproteinase 2
  • Horse(100033948) matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)
  • Domestic Rabbit(100009000) matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)
  • domestic cat(101098838) matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)
  • fruit fly(35997) Matrix metalloproteinase 2

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ELISA

Número do produto
Descrição
Espécies
Human MMP-2 ELISA Kit, for serum, plasma, cell culture supernatant,
Espécies
human
Mouse MMP-2 ELISA Kit, for serum, plasma and cell culture supernatant,
Espécies
mouse
Rat MMP-2 ELISA, for serum, plasma and cell culture supernatants,
Espécies
rat

Antibodies

Número do produto
Descrição
Reatividade de espécies
Aplicação
Anticorpo anti-MMP-2, a.a. 468-483 hMMP2, clone 42-5D11, clone 42-5D11, Chemicon®, from mouse,
Reatividade de espécies
bovine, horse, human, mouse, pig, rabbit, rat
Aplicação
ELISA
immunohistochemistry

western blot
Anti-MMP2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reatividade de espécies
human
Aplicação
immunohistochemistry
western blot
Anti-MMP-2 (Ab-3) Mouse mAb (42-5D11), liquid, clone 42-5D11, Calbiochem®,
Reatividade de espécies
bovine, human, mouse, rat
Aplicação
Anti-MMP-2 Antibody, pro and active form, clone VB3, clone VB3, Chemicon®, from mouse,
Reatividade de espécies
human
Aplicação
ELISA
immunofluorescence

western blot
Anti- MMP2 antibody produced in rabbit, ,
Reatividade de espécies
human, mouse, rat
Aplicação
immunohistochemistry
western blot

Small Molecule - Inhibitor

Número do produto
Descrição
Espécies
Marimastat, ≥98% (HPLC),
Espécies
human, rat, mouse
CP-101537, ≥98% (HPLC),
Espécies
human, rat, mouse
CP-471474, ≥98% (HPLC),
Espécies
human, rat, mouse
PD166793 hydrate, ≥98% (HPLC),
Espécies
human, rat, mouse

Proteins

Número do produto
Descrição
Espécies
MMP-2 human, recombinant, expressed in E. coli, ≥98% (SDS-PAGE), ≥98% (HPLC), suitable for cell culture,
Espécies
human
Matrix Metalloproteinase-2 human, >90% (SDS-PAGE), recombinant, expressed in NSO cells, lyophilized powder,
Espécies
human
Matrix Metalloproteinase-2 from mouse, recombinant, expressed in NSO cells, >95% (SDS-PAGE), buffered aqueous glycerol solution,
Espécies
mouse, rat

esiRNA

Número do produto
Descrição
Espécies
MISSION® esiRNA, targeting mouse Mmp2,
Espécies
mouse
MISSION® esiRNA, targeting human MMP2,
Espécies
human