HSPG2
heparan sulfate proteoglycan 2
Sinônimos:
HSPG, PLC, PRCAN, SJA, SJS, SJS1
Espécies:
Human HSPG2 (3339), Mouse Hspg2 (15530), Rat Hspg2 (117511), domestic guinea pig Hspg2 (100718406), naked mole-rat Hspg2 (101700294), cow HSPG2 (444872), Domestic Rabbit HSPG2 (100340334), chicken HSPG2 (429806), Horse HSPG2 (100071701), sheep HSPG2 (101122677) ...Mais
ID UniProtKB:
ID do gene:
- Human(3339) Summary: This gene encodes the perlecan protein, which consists of a core protein to which three long chains of glycosaminoglycans (heparan sulfate or chondroitin sulfate) are attached. The perlecan protein is a large multidomain proteoglycan that binds to and cross-links many extracellular matrix components and cell-surface molecules. It has been shown that this protein interacts with laminin, prolargin, collagen type IV, FGFBP1, FBLN2, FGF7 and Transthyretin, etc. and plays essential roles in multiple biological activities. Perlecan is a key component of the vascular extracellular matrix, where it helps to maintain the endothelial barrier function. It is a potent inhibitor of smooth muscle cell proliferation and is thus thought to help maintain vascular homeostasis. It can also promote growth factor (e.g., FGF2) activity and thus stimulate endothelial growth and re-generation. It is a major component of basement membranes, where it is involved in the stabilization of other molecules as well as being involved with glomerular permeability to macromolecules and cell adhesion. Mutations in this gene cause Schwartz-Jampel syndrome type 1, Silverman-Handmaker type of dyssegmental dysplasia, and Tardive dyskinesia.[provided by RefSeq, Mar 2010]
- Mouse(15530) perlecan (heparan sulfate proteoglycan 2)
- Rat(117511) heparan sulfate proteoglycan 2
- domestic guinea pig(100718406) heparan sulfate proteoglycan 2
- naked mole-rat(101700294) heparan sulfate proteoglycan 2
- cow(444872) heparan sulfate proteoglycan 2
- Domestic Rabbit(100340334) heparan sulfate proteoglycan 2
- chicken(429806) heparan sulfate proteoglycan 2
- Horse(100071701) heparan sulfate proteoglycan 2
- sheep(101122677) heparan sulfate proteoglycan 2
- sheep(100294588) heparan sulfate proteoglycan 2
- domestic cat(101094520) heparan sulfate proteoglycan 2
- Zebrafish(565429) heparan sulfate proteoglycan 2
- dog(403440) heparan sulfate proteoglycan 2
Custom & Knockdown Gene Products
siRNA
Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.
shRNA
Shop the largest, most validated shRNA collection and build your own clone sets.
Custom Gene Products
We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.
ELISA
Número do produto
Descrição
Espécies
Antibodies
Número do produto
Descrição
Reatividade de espécies
Aplicação
Anticorpo anti-proteoglicano de sulfato de heparan (Perlecan), clone A7L6, clone A7L6, from rat,
Reatividade de espécies
human
Aplicação
immunocytochemistry
immunohistochemistry
immunoprecipitation (IP)
western blot
immunohistochemistry
immunoprecipitation (IP)
western blot
Anti-Heparin/Heparan Sulfate Antibody, clone T320.11, clone T320.11, Chemicon®, from mouse,
Reatividade de espécies
mammals
Aplicação
ELISA
radioimmunoassay
western blot
radioimmunoassay
western blot
Anti-Heparan Sulfate Proteoglycan (Perlecan) Antibody, clone 5D7-2E4, clone 5D7-2E4, from mouse,
Reatividade de espécies
human
Aplicação
immunocytochemistry
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-HSPG2 antibody produced in rabbit, affinity isolated antibody,
Reatividade de espécies
human, mouse
Aplicação
immunohistochemistry
western blot
western blot
Anti-Estrogen Receptor Antibody, clone B10, ascites fluid, clone B10, Chemicon®,
Reatividade de espécies
human, rat
Aplicação
ELISA
immunohistochemistry
western blot
immunohistochemistry
western blot
Proteins
Número do produto
Descrição
Espécies
Gel de MEC, growth-factor reduced, without phenol red, liquid, BioReagent, suitable for cell culture,
Espécies
mouse