GRN
granulin
Sinônimos:
CLN11, GEP, GP88, PCDGF, PEPI, PGRN
Espécies:
Human GRN (2896), Mouse Grn (14824), Rat Grn (29143), fruit fly grn (40962), dog GRN (480501), Horse GRN (100051035), domestic cat GRN (101100680), cow GRN (767942), sheep GRN (101115470), Domestic Rabbit GRN (100349528) ...Mais
ID UniProtKB:
ID do gene:
- Human(2896) Summary: Granulins are a family of secreted, glycosylated peptides that are cleaved from a single precursor protein with 7.5 repeats of a highly conserved 12-cysteine granulin/epithelin motif. The 88 kDa precursor protein, progranulin, is also called proepithelin and PC cell-derived growth factor. Cleavage of the signal peptide produces mature granulin which can be further cleaved into a variety of active, 6 kDa peptides. These smaller cleavage products are named granulin A, granulin B, granulin C, etc. Epithelins 1 and 2 are synonymous with granulins A and B, respectively. Both the peptides and intact granulin protein regulate cell growth. However, different members of the granulin protein family may act as inhibitors, stimulators, or have dual actions on cell growth. Granulin family members are important in normal development, wound healing, and tumorigenesis. [provided by RefSeq, Jul 2008]
- Mouse(14824) granulin
- Rat(29143) granulin
- fruit fly(40962) grain
- dog(480501) granulin
- Horse(100051035) granulin
- domestic cat(101100680) granulin
- cow(767942) granulin
- sheep(101115470) granulin
- Domestic Rabbit(100349528) granulin
- domestic guinea pig(100135533) granulin
- naked mole-rat(101715753) granulin
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ELISA
Antibodies
Número do produto
Descrição
Reatividade de espécies
Aplicação
Anti-GRN antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reatividade de espécies
human, mouse, rat
Aplicação
immunofluorescence
immunohistochemistry
immunohistochemistry
Anti-Granulin (C-terminal) antibody produced in rabbit, ~1.0 mg/mL, affinity isolated antibody,
Reatividade de espécies
human
Aplicação
immunofluorescence
western blot
western blot
Anti-GRN antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
Reatividade de espécies
human
Aplicação
ELISA
western blot
western blot
Anti-Progranulin/GRN Antibody, clone 8H10, clone 8H10, from rat,
Reatividade de espécies
mouse
Aplicação
immunohistochemistry
western blot
western blot
Anti-GRN antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reatividade de espécies
human
Aplicação
immunofluorescence
immunohistochemistry
immunohistochemistry
Proteins
Número do produto
Descrição
Espécies
Progranulin human, recombinant, expressed in HEK 293 cells, untagged, >95% (SDS-PAGE),
Espécies
human
Progranulin mouse, recombinant, expressed in HEK 293 cells, untagged, >95% (SDS-PAGE),
Espécies
mouse
Granulin C human, recombinant, expressed in E. coli, His tagged, >90% (SDS-PAGE),
Espécies
human
Progranulin mouse, recombinant, expressed in HEK 293 cells, FLAG® tagged, >95% (SDS-PAGE),
Espécies
mouse
Progranulin rat, recombinant, expressed in HEK 293 cells, FLAG® tagged, >95% (SDS-PAGE),
Espécies
rat