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Merck

GRIK2

glutamate receptor, ionotropic, kainate 2

Sinônimos:
EAA4, GLR6, GLUK6, GLUR6, GluK2, MRT6
Espécies:
ID UniProtKB:
ID do gene:
  • Human(2898) Summary: Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. This gene product belongs to the kainate family of glutamate receptors, which are composed of four subunits and function as ligand-activated ion channels. The subunit encoded by this gene is subject to RNA editing at multiple sites within the first and second transmembrane domains, which is thought to alter the structure and function of the receptor complex. Alternatively spliced transcript variants encoding different isoforms have also been described for this gene. Mutations in this gene have been associated with autosomal recessive mental retardation. [provided by RefSeq, Jul 2008]
  • Mouse(14806) glutamate receptor, ionotropic, kainate 2 (beta 2)
  • Rat(54257) glutamate receptor, ionotropic, kainate 2
  • chicken(428628) glutamate receptor, ionotropic, kainate 2
  • dog(481938) glutamate receptor, ionotropic, kainate 2
  • Thale Cress(836176) geminivirus rep interacting kinase 2
  • Zebrafish(556013) glutamate receptor, ionotropic, kainate 2
  • cow(615226) glutamate receptor, ionotropic, kainate 2
  • naked mole-rat(101697577) glutamate receptor, ionotropic, kainate 2
  • domestic guinea pig(100733104) glutamate receptor, ionotropic, kainate 2
  • sheep(101122701) glutamate receptor, ionotropic, kainate 2

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Small Molecule - Agonist

Número do produto
Descrição
Espécies
L-Glutamic acid hydrochloride, ,
Espécies
human
(±)-AMPA, solid,
Espécies
rat
(S)-AMPA, ≥97%,
Espécies
mouse, human, rat
Kainic acid monohydrate, ≥99% (TLC),
Espécies
human, mouse, rat
(Aminomethyl)phosphonic acid, 99%,
Espécies
rat, human

Small Molecule - Antagonist

Número do produto
Descrição
Espécies
CNQX, ≥98% (HPLC), solid,
Espécies
rat
NBQX disodium salt hydrate, ≥98% (HPLC),
Espécies
human
DNQX, ≥98% (TLC),
Espécies
mouse, rat, human
(±)-AMPA, solid,
Espécies
rat
(S)-AMPA, ≥97%,
Espécies
mouse, human, rat

Antibodies

Número do produto
Descrição
Reatividade de espécies
Aplicação
Anti-GluR6/7 Antibody, clone NL9, rabbit monoclonal, culture supernatant, clone NL904, Upstate®,
Reatividade de espécies
human, mouse, rat
Aplicação
immunoprecipitation (IP)
western blot
Anti-GRIK2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reatividade de espécies
human, mouse, rat
Aplicação
immunohistochemistry
western blot
Anti-GRIK2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reatividade de espécies
human
Aplicação
immunohistochemistry
Anti-GRIK2 antibody produced in rabbit, affinity isolated antibody,
Reatividade de espécies
bovine, dog, guinea pig, horse, human, mouse, rabbit, rat
Aplicação
western blot
Anti-GRIK2 Antibody, clone 4B4L9, Rabbit Monoclonal, ,
Reatividade de espécies
human, rat
Aplicação
immunohistochemistry
western blot

Small Molecule - Mixed Agonist/Antagonist

Número do produto
Descrição
Espécies
(±)-AMPA, solid,
Espécies
rat
Kainic acid monohydrate, ≥99% (TLC),
Espécies
human, mouse, rat
L-Glutamic acid, ReagentPlus®, ≥99% (HPLC),
Espécies
rat, human
L-Glutamic acid, from non-animal source, meets EP testing specifications, suitable for cell culture, 98.5-100.5%,
Espécies
rat, human
L-Glutamic acid, BioUltra, ≥99.5% (NT),
Espécies
rat, human

esiRNA

Número do produto
Descrição
Espécies
MISSION® esiRNA, targeting human GRIK2 (1),
Espécies
human
MISSION® esiRNA, targeting human GRIK2 (2),
Espécies
human